Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | BRAF | P15056 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | CSF1R | P07333 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22891788 | 0.82 | GPR35 (0.36) | TAS2R14GAAMEN1KMT2ABRAF | |
| SCHEMBL22891786 | 0.79 | NPSR1 (0.49) | GAAMEN1KMT2ALMNAHTT | |
| SCHEMBL29669997 | 0.79 | NPSR1 (0.49) | GAAMEN1KMT2ALMNAHTT | |
| SCHEMBL22891791 | 0.71 | ADRB2 (0.34) | HTR7NPC1RAB9AALDH1A1 | |
| SCHEMBL19354448 | 0.70 | ADRB2 (0.53) | KMT2ANPSR1NPC1RAB9A | |
| SCHEMBL22891790 | 0.69 | HTT (0.44) | GAAMEN1KMT2AHTTNPSR1 | |
| SCHEMBL29670040 | 0.69 | HTT (0.44) | GAAMEN1KMT2AHTTNPSR1 | |
| SCHEMBL19321862 | 0.69 | HTR7 (0.49) | GAAMEN1KMT2ALMNAHTR7 | |
| SCHEMBL7433225 | 0.67 | ADRB2 (0.54) | LMNAHTR7CYP1A2CYP3A4NPC1 | |
| SCHEMBL25805521 | 0.66 | DDR2 (0.58) | TAS2R14GAALMNAMRGPRX4DDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021007474-A1 | PHENYL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR THERAPEUTIC APPLICATIONS | CURA THERAPEUTICS, LLC (US) | 2021-01-14 | — | — | WO | disclosed |