Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | DUSP5 | Q16690 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Silver SCHEMBL9550115 | 0.94 | CA2 (0.52) | CA2CA1LMNATDP1KMT2A | |
| Potassium Ion SCHEMBL2785770 | 0.94 | CA2 (0.52) | CA2CA1LMNATDP1KMT2A | |
| SCHEMBL128235 | 0.94 | LMNA (0.56) | CA2CA1LMNATDP1KMT2A | |
| SCHEMBL9550124 | 0.94 | CA2 (0.52) | CA2CA1LMNATDP1KMT2A | |
| Potassium Ion SCHEMBL30400899 | 0.87 | LMNA (0.52) | CA2CA1LMNATDP1KMT2A | |
| SCHEMBL3942912 | 0.87 | LMNA (0.52) | CA2CA1LMNATDP1KMT2A | |
| SCHEMBL29458759 | 0.87 | LMNA (0.52) | CA2CA1LMNATDP1KMT2A | |
| Potassium Ion SCHEMBL135380 | 0.87 | LMNA (0.52) | CA2CA1LMNATDP1KMT2A | |
| Potassium Ion SCHEMBL1415904 | 0.84 | ALDH1A1 (0.48) | CA2CA1LMNATDP1KMT2A | |
| SCHEMBL22204350 | 0.84 | ALDH1A1 (0.55) | CA2CA1LMNATDP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070244191-A1 | Strontium salts of sulphonic acids, a process for their preparation and pharmaceutical compositions containing them | LES LABORATOIRES SERVIER (FR) | 2007-10-18 | — | — | US | claimed |
| US-7999009-B2 | Strontium salts of sulphonic acids, a process for their preparation and pharmaceutical compositions containing them | LES LABORATOIRES SERVIER (FR) | 2011-08-16 | — | — | US | disclosed |
| US-20070244191-A1 | Strontium salts of sulphonic acids, a process for their preparation and pharmaceutical compositions containing them | LES LABORATOIRES SERVIER (FR) | 2007-10-18 | — | — | US | disclosed |