Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | HTR6 | P50406 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL135380 | 1.00 | LMNA (0.52) | LMNASMN1; SMN2MAPTKMT2AKDM4E | |
| Potassium Ion SCHEMBL1415904 | 0.96 | ALDH1A1 (0.48) | LMNASMN1; SMN2MAPTKMT2AKDM4E | |
| SCHEMBL3942912 | 0.95 | LMNA (0.52) | LMNASMN1; SMN2MAPTKMT2AKDM4E | |
| SCHEMBL29458759 | 0.95 | LMNA (0.52) | LMNASMN1; SMN2MAPTKMT2AKDM4E | |
| Potassium Ion SCHEMBL132363 | 0.94 | HTR6 (0.58) | LMNASMN1; SMN2MAPTKMT2AKDM4E | |
| Potassium Ion SCHEMBL29376363 | 0.94 | HTR6 (0.58) | LMNASMN1; SMN2MAPTKMT2AKDM4E | |
| Potassium Ion SCHEMBL2785770 | 0.93 | CA2 (0.52) | LMNASMN1; SMN2MAPTKMT2AKDM4E | |
| SCHEMBL1416146 | 0.89 | HTR6 (0.58) | LMNASMN1; SMN2MAPTKMT2AKDM4E | |
| SCHEMBL9550124 | 0.87 | CA2 (0.52) | LMNASMN1; SMN2MAPTKMT2AKDM4E | |
| SCHEMBL128235 | 0.87 | LMNA (0.56) | LMNASMN1; SMN2MAPTKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119816558-A | Polycarbonate resin composition and molded article comprising the same | 帝人株式会社 | 2025-04-11 | — | — | CN | disclosed |
| CN-119013349-A | Polycarbonate resin composition and molded article | 帝人株式会社 | 2024-11-22 | — | — | CN | disclosed |
| CN-118922495-A | Aromatic polycarbonate resin composition and molded article thereof | 帝人株式会社 | 2024-11-08 | — | — | CN | disclosed |
| CN-118696093-A | Flame retardant polycarbonate compositions | 科思创德国股份有限公司 | 2024-09-24 | — | — | CN | disclosed |
| CN-116096818-A | Hydrolysis-resistant polycarbonate compositions | 科思创德国股份有限公司 | 2023-05-09 | — | — | CN | disclosed |