SCHEMBL128235

SCHEMBL128235

O=S(=O)([O-])c1cccc(S(=O)(=O)[O-])c1.[Na+].[Na+]

nearest known ligand 0.59

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 known ✓ P00915 2/20 0.52
CA2 known ✓ P00918 2/20 0.52
CA12 known ✓ O43570 1/20 0.39
CA4 known ✓ P22748 1/20 0.39
LMNA P02545 3/20 0.56
TDP1 Q9NUW8 1/20 0.56
DUSP5 Q16690 3/20 0.44
KMT2A Q03164 4/20 0.43
PTPN1 P18031 3/20 0.43
POLB P06746 1/20 0.43
APOBEC3A P31941 1/20 0.43
CASP6 P55212 1/20 0.43
CTDSP1 Q9GZU7 1/20 0.43
APOBEC3G Q9HC16 1/20 0.43
KDM4E B2RXH2 1/20 0.42
MEN1 O00255 1/20 0.42
NPC1 O15118 1/20 0.42
MAPT P10636 1/20 0.42
HPGD P15428 1/20 0.42
RAB9A P51151 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Silver SCHEMBL9550115 0.94 CA2 (0.52) LMNATDP1CA1CA2DUSP5
SCHEMBL2289282 0.94 CA2 (0.52) LMNATDP1CA1CA2DUSP5
SCHEMBL9550124 0.94 CA2 (0.52) LMNATDP1CA1CA2DUSP5
Potassium Ion SCHEMBL2785770 0.94 CA2 (0.52) LMNATDP1CA1CA2DUSP5
SCHEMBL29458759 0.93 LMNA (0.52) LMNATDP1CA1CA2DUSP5
SCHEMBL3942912 0.93 LMNA (0.52) LMNATDP1CA1CA2DUSP5
SCHEMBL22204350 0.89 ALDH1A1 (0.55) LMNATDP1CA1CA2DUSP5
Potassium Ion SCHEMBL30400899 0.87 LMNA (0.52) LMNATDP1CA1CA2KMT2A
Potassium Ion SCHEMBL135380 0.87 LMNA (0.52) LMNATDP1CA1CA2KMT2A
SCHEMBL15509797 0.87 LMNA (0.50) LMNATDP1CA1CA2DUSP5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 491 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250049674-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING AT LEAST A MEROCYANINE AND A HYDROTROPE L'OREAL (FR) 2025-02-13 US claimed
US-20240423888-A1 COSMETIC AND/OR DERMATOLOGICAL COMPOSITION COMPRISING AT LEAST ONE MEROCYANINE AND AT LEAST ASCORBIC ACID AND/OR A DERIVATIVE THEREOF L'OREAL (FR) 2024-12-26 US claimed
US-12146184-B2 Blood glucose measurement reagent, sensor chip, and blood glucose meter set TERUMO KABUSHIKI KAISHA (JP) 2024-11-19 US claimed
CN-118871078-A Cosmetic or dermatological composition comprising at least a merocyanine and a hydrotrope 欧莱雅 2024-10-29 CN claimed
EP-4447895-A1 COSMETIC AND/OR DERMATOLOGICAL COMPOSITION COMPRISING AT LEAST ONE MEROCYANINE AND AT LEAST ASCORBIC ACID AND/OR A DERIVATIVE THEREOF L'OREAL (FR) 2024-10-23 EP claimed
CN-118804735-A Cosmetic and/or dermatological composition comprising at least one merocyanine and at least ascorbic acid and/or derivatives thereof 莱雅公司 2024-10-18 CN claimed
CN-114835612-B Synthetic method for preparing m-aminophenol 青岛科技大学 2024-09-24 CN claimed
CN-111788472-B Method, reagent and chip for determining concentration of analyte in biological sample 泰尔茂株式会社 2023-12-15 CN claimed
US-11719701-B2 Blood glucose level measuring chip and blood glucose level measuring device set TERUMO KABUSHIKI KAISHA (JP) 2023-08-08 US claimed
WO-2023110772-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING AT LEAST A MEROCYANINE AND A HYDROTROPE L'OREAL (FR) 2023-06-22 WO claimed
US-20030195134-A1 Detergent granule comprising a nonionic surfactant and a hydrotrope THE PROCTER & GAMBLE COMPANY 2003-10-16 US claimed
EP-1352951-A1 Detergent granule comprising a nonionic surfactant and a hydrotrope The Procter & Gamble Company (US) 2003-10-15 EP claimed
US-5958368-A HYDROTHERMAL REACTION OF ALKYLTRIMETHYLAMMONIUM HALIDE AND WATER SOLUBLE ORGANIC SALTS; CALCINING RESULTING PRECIPITATE; RANDOMLY INTERCONNECTED CHANNELS OF UNIFORM DIAMETER ALLOW DIFFUSION OF REACTANTS; IMPROVED HYDROTHERMAL STABILITY YUKONG LIMITED (KR) 1999-09-28 US claimed
US-5942208-A STABILIZING THE HYDROTHERMAL REACTION OF ZEOLITE MCM-41 BY MIXING ALKYLTRIMETHYLAMMONIUM SURFACTANT; SUBJECTING TO HYDROTHERMAL REACTION; MIXING ORGANIC OR INORGANIC WATER-SOLUBLE SALTS; HYDROTHERMAL REACTION; CALCINING YU KONG LIMITED (KR) 1999-08-24 US claimed
EP-0661965-B1 HAIR CONDITIONING STYLE CONTROL SHAMPOO COLGATE PALMOLIVE CO (US) 1999-06-30 EP claimed
EP-0400657-B1 Process for developing of ps plates requiring no dampening water FUJI PHOTO FILM CO LTD (JP) 1996-03-27 EP claimed
US-5500668-A INK JET PRINTING XEROX CORPORATION (US) 1996-03-19 US claimed
EP-0661965-A1 HAIR CONDITIONING STYLE CONTROL SHAMPOO Colgate-Palmolive Company (US) 1995-07-12 EP claimed
WO-1994006410-A1 HAIR CONDITIONING STYLE CONTROL SHAMPOO COLGATE-PALMOLIVE COMPANY (US) 1994-03-31 WO claimed
US-5290665-A Process for developing PS plate requiring no dampening water wherein the developer comprises, water, a solubilizer and an ethylene glycol mono(alkyl C6 -C8) ether derivative FUJI PHOTO FILM CO., LTD. (JP) 1994-03-01 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240423888-A1 COSMETIC AND/OR DERMATOLOGICAL COMPOSITION COMPRISING AT LEAST ONE MEROCYANINE AND AT LEAST ASCORBIC ACID AND/OR A DERIVATIVE THEREOF KRT18, PROC, DSC1 CA1 1327/4885CA2 797/4885CA12 547/4885
US-20250049674-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING AT LEAST A MEROCYANINE AND A HYDROTROPE NAPRT, NAMPT, NNMT CA1 440/4885CA2 393/4885CA12 961/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.