SCHEMBL2289311

SCHEMBL2289311

O=C(OC1CCN(C(=O)c2c3oc4ccccc4nc-3ccc2=O)CC1)ON1C(=O)CCC1=O

nearest known ligand 0.39

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LMNA P02545 6/20 0.39
HTR2B P41595 1/20 0.37
MAPT P10636 1/20 0.36
THRB P10828 2/20 0.35
RBP4 P02753 1/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
ALDH1A1 P00352 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
HCRTR1 O43613 2/20 0.35
HCRTR2 O43614 2/20 0.35
POLB P06746 1/20 0.35
USP2 O75604 1/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
CCNE1 P24864 1/20 0.34
CDK2 P24941 1/20 0.34
GSK3B P49841 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3496983 0.88 LMNA (0.40) LMNAHTR2BMAPTTHRBRBP4
SCHEMBL2185384 0.86 LMNA (0.46) LMNAHTR2BMAPTTHRBRBP4
SCHEMBL9051488 0.80 LMNA (0.49) LMNAHTR2BMAPTTHRBRBP4
SCHEMBL2342936 0.73 ALDH1A1 (0.42) LMNAHTR2BMAPTSMN1; SMN2ALDH1A1
SCHEMBL9295725 0.73 KMT2A (0.32) LMNAMAPTSMN1; SMN2ALDH1A1NPSR1
Trifluoroacetic Acid SCHEMBL9295868 0.70 ATR (0.39) LMNAHTR2BTHRBRBP4SMN1; SMN2
SCHEMBL1104938 0.68 APP (0.44) ALDH1A1MEN1KMT2A
SCHEMBL1513840 0.68 MEN1 (0.43) LMNAMAPTSMN1; SMN2ALDH1A1L3MBTL1
Phosphoric Acid SCHEMBL1513833 0.65 RAB9A (0.42) LMNAMAPTSMN1; SMN2ALDH1A1L3MBTL1
SCHEMBL12714431 0.64 ESR1 (0.40)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3353316-B1 METHODS OF PREDICTION OF WOUND HEALING WOUNDCHEK LABORATORIES INC (US) 2024-01-10 EP disclosed
US-20200392557-A1 METHODS OF PREDICTION OF WOUND HEALING WOUNDCHEK LABORATORIES (US), INC. (US) 2020-12-17 US disclosed
US-10774363-B2 Methods of prediction of wound healing WOUNDCHEK LABORATORIES (US), INC. (US) 2020-09-15 US disclosed
US-20180346959-A1 Methods of Prediction of Wound Healing WOUNDCHEK LABORATORIES (US), INC. 2018-12-06 US disclosed
EP-3353316-A1 METHODS OF PREDICTION OF WOUND HEALING Woundchek Laboratories, Inc. (US) 2018-08-01 EP disclosed
WO-2017053931-A1 METHODS OF PREDICTION OF WOUND HEALING WoundChek Laboratories, Inc. (US) 2017-03-30 WO disclosed
US-20140370535-A1 STERILITY INDICATING BIOLOGICAL COMPOSITIONS, ARTICLES AND METHODS 3M INNOVATIVE PROPERTIES CO (US) 2014-12-18 US disclosed
US-20110195442-A1 STERILITY INDICATING BIOLOGICAL COMPOSITIONS, ARTICLES AND METHODS 3M INNOVATIVE PROPERTIES 2011-08-11 US disclosed