Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 7/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RBP4 | P02753 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2289311 | 0.88 | LMNA (0.39) | LMNARBP4HTR2BL3MBTL1USP2 | |
| SCHEMBL9051488 | 0.85 | LMNA (0.49) | LMNARAB9AHTTRBP4HTR2B | |
| SCHEMBL2185384 | 0.80 | LMNA (0.46) | LMNARBP4HTR2BL3MBTL1USP2 | |
| SCHEMBL2342936 | 0.75 | ALDH1A1 (0.42) | LMNARAB9ANPC1HTTHTR2B | |
| SCHEMBL9295725 | 0.74 | KMT2A (0.32) | LMNARAB9ANPC1PKML3MBTL1 | |
| Trifluoroacetic Acid SCHEMBL9295868 | 0.72 | ATR (0.39) | LMNAHTTRBP4HTR2BPKM | |
| SCHEMBL1104938 | 0.70 | APP (0.44) | TDP1ALDH1A1GAA | |
| SCHEMBL1513840 | 0.69 | MEN1 (0.43) | LMNARAB9ANPC1PKML3MBTL1 | |
| Phosphoric Acid SCHEMBL1513833 | 0.66 | RAB9A (0.42) | LMNARAB9ANPC1PKML3MBTL1 | |
| SCHEMBL12714431 | 0.66 | ESR1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5304645-A | Colored or fluorescent labels | BOEHRINGER MANNHEIM GMBH (DE) | 1994-04-19 | — | — | US | claimed |
| US-5242842-A | Precipitation | AXIS RESEARCH AS (NO) | 1993-09-07 | — | — | US | claimed |
| US-9140710-B2 | Transcobalamin II assay method | AXIS-SHIELD ASA (NO) | 2015-09-22 | — | — | US | disclosed |
| WO-2014033258-A1 | GLYCATED HAEMOGLOBIN ASSAY METHOD | AXIS-SHIELD ASA (NO) | 2014-03-06 | — | — | WO | disclosed |
| US-20100099129-A1 | Transcobalamin II assay method | AXIS - SHIELD ASA (NO) | 2010-04-22 | — | — | US | disclosed |
| EP-1381869-B1 | HAEMOGLOBIN ASSAY | AXIS SHIELD ASA (NO) | 2008-07-30 | — | — | EP | disclosed |
| US-7374943-B2 | Haemoglobin assay | AXIS-SHIELD USA (NO) | 2008-05-20 | — | — | US | disclosed |
| US-7344849-B2 | Assay | AXIS-SHIELD ASA (NO) | 2008-03-18 | — | — | US | disclosed |
| US-7279283-B1 | Cobalamin assay | AXIS-SHIELD ASA (NO) | 2007-10-09 | — | — | US | disclosed |
| EP-1443328-B1 | Cobalamin assay | AXIS SHIELD ASA (NO) | 2007-05-23 | — | — | EP | disclosed |
| EP-1257830-B1 | ASSAY FOR MEASURING HOLO-TRANSCOBALAMIN AND FOLATE | AXIS SHIELD ASA (NO) | 2007-04-18 | — | — | EP | disclosed |
| US-5304645-A | Colored or fluorescent labels | BOEHRINGER MANNHEIM GMBH (DE) | 1994-04-19 | — | — | US | disclosed |
| US-5242842-A | Precipitation | AXIS RESEARCH AS (NO) | 1993-09-07 | — | — | US | disclosed |
| EP-0557350-A1 | ASSAY FOR GLYCATED BLOOD PROTEINS. | AXIS RESEARCH (NO) | 1993-09-01 | — | — | EP | disclosed |
| EP-0535162-A1 | ANALYTE VARIANT ANALYSIS. | AXIS RESEARCH (NO) | 1993-04-07 | — | — | EP | disclosed |
| WO-1992008984-A1 | ASSAY FOR GLYCATED BLOOD PROTEINS | AXIS RESEARCH AS (NO) | 1992-05-29 | — | — | WO | disclosed |
| EP-0471774-A1 | GLYCOSYLATED HAEMOGLOBIN ASSAY. | AXIS RESEARCH (NO) | 1992-02-26 | — | — | EP | disclosed |
| WO-1991019983-A1 | ANALYTE VARIANT ANALYSIS | AXIS RESEARCH AS (NO) | 1991-12-26 | — | — | WO | disclosed |
| WO-1990013818-A1 | GLYCOSYLATED HAEMOGLOBIN ASSAY | AXIS RESEARCH AS (NO) | 1990-11-15 | — | — | WO | disclosed |
| US-4954630-A | COLORIMETRIC OR FLUORESCENT ANALYSIS | BOEHRINGER MANNHEIM GMBH (DE) | 1990-09-04 | — | — | US | disclosed |