Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTO1 | P78417 | 2/20 | 0.52 |
| ▸ | P2RX4 | Q99571 | 6/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | KCNJ6 | P48051 | 2/20 | 0.44 |
| ▸ | KCNJ5 | P48544 | 2/20 | 0.44 |
| ▸ | KCNJ3 | P48549 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.44 |
| ▸ | ACKR3 | P25106 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.42 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19576777 | 0.88 | P2RX4 (0.61) | P2RX4ROCK2 | |
| SCHEMBL19576873 | 0.86 | KCNJ5 (0.60) | GSTO1P2RX4ALDH1A1LMNAKCNJ6 | |
| SCHEMBL20929060 | 0.84 | P2RX4 (0.51) | GSTO1P2RX4ALDH1A1LMNAKCNJ6 | |
| SCHEMBL19551715 | 0.81 | P2RX4 (0.47) | GSTO1P2RX4ALDH1A1LMNAKCNJ6 | |
| SCHEMBL19551717 | 0.81 | P2RX4 (0.47) | GSTO1P2RX4ALDH1A1LMNAKCNJ6 | |
| SCHEMBL19576776 | 0.81 | NPC1 (0.52) | GSTO1P2RX4ALDH1A1LMNAKCNJ6 | |
| SCHEMBL24686030 | 0.78 | ROCK2 (0.49) | P2RX4ALDH1A1LMNAKCNJ5KCNJ3 | |
| SCHEMBL24687088 | 0.78 | ROCK2 (0.49) | P2RX4ALDH1A1LMNAKCNJ5KCNJ3 | |
| SCHEMBL24686679 | 0.76 | RECQL (0.47) | P2RX4ALDH1A1LMNAKCNJ5KCNJ3 | |
| SCHEMBL19576907 | 0.75 | GSTO1 (0.42) | GSTO1P2RX4ALDH1A1LMNAKCNJ6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3763704-A1 | AROMATIC SULFONAMIDE DERIVATIVES | Bayer Pharma Aktiengesellschaft (DE) | 2021-01-13 | — | — | EP | disclosed |