Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTO1 | P78417 | 3/20 | 0.42 |
| ▸ | P2RX4 | Q99571 | 5/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | ACKR3 | P25106 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.35 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.35 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.34 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22894329 | 0.75 | GSTO1 (0.52) | GSTO1P2RX4ROCK2ACKR3ALDH1A1 | |
| SCHEMBL19576777 | 0.67 | P2RX4 (0.61) | P2RX4ROCK2 | |
| SCHEMBL20929060 | 0.66 | P2RX4 (0.51) | GSTO1P2RX4ROCK2ACKR3ALDH1A1 | |
| SCHEMBL19551715 | 0.65 | P2RX4 (0.47) | GSTO1P2RX4ROCK2ACKR3ALDH1A1 | |
| SCHEMBL19551717 | 0.65 | P2RX4 (0.47) | GSTO1P2RX4ROCK2ACKR3ALDH1A1 | |
| SCHEMBL24686679 | 0.64 | RECQL (0.47) | P2RX4ROCK2ACKR3ALDH1A1LMNA | |
| SCHEMBL24687088 | 0.64 | ROCK2 (0.49) | P2RX4ROCK2ACKR3ALDH1A1LMNA | |
| SCHEMBL30403105 | 0.63 | ANO1 (0.49) | P2RX4ROCK2ANO1 | |
| SCHEMBL19576873 | 0.63 | KCNJ5 (0.60) | GSTO1P2RX4ALDH1A1LMNAPOLB | |
| SCHEMBL12824945 | 0.62 | MEN1 (0.54) | P2RX4ROCK2ACKR3ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3458443-B1 | AROMATIC SULFONAMIDE DERIVATIVES | Bayer Pharma AG (DE) | 2020-08-19 | — | — | EP | disclosed |
| WO-2017191000-A1 | AROMATIC SULFONAMIDE DERIVATIVES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2017-11-09 | — | — | WO | disclosed |