Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX4 | Q99571 | 10/20 | 0.51 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.44 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | KCNJ6 | P48051 | 2/20 | 0.41 |
| ▸ | KCNJ5 | P48544 | 2/20 | 0.41 |
| ▸ | KCNJ3 | P48549 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | ACKR3 | P25106 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19576777 | 0.87 | P2RX4 (0.61) | P2RX4ROCK2 | |
| SCHEMBL20929094 | 0.86 | P2RX4 (0.57) | P2RX4ALDH1A1LMNAKCNJ6KCNJ5 | |
| SCHEMBL19551715 | 0.84 | P2RX4 (0.47) | P2RX4ROCK2GSTO1ALDH1A1LMNA | |
| SCHEMBL19551717 | 0.84 | P2RX4 (0.47) | P2RX4ROCK2GSTO1ALDH1A1LMNA | |
| SCHEMBL22894329 | 0.84 | GSTO1 (0.52) | P2RX4ROCK2GSTO1ALDH1A1LMNA | |
| SCHEMBL20929119 | 0.82 | RAB9A (0.51) | P2RX4GSTO1ALDH1A1LMNAKCNJ6 | |
| SCHEMBL24687088 | 0.78 | ROCK2 (0.49) | P2RX4ROCK2ALDH1A1LMNAKCNJ5 | |
| SCHEMBL24686030 | 0.78 | ROCK2 (0.49) | P2RX4ROCK2ALDH1A1LMNAKCNJ5 | |
| SCHEMBL24686059 | 0.73 | P2RX4 (0.60) | P2RX4 | |
| SCHEMBL29852110 | 0.73 | P2RX4 (0.60) | P2RX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10844016-B2 | Aromatic sulfonamide derivatives | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2020-11-24 | — | — | US | disclosed |
| US-20190119210-A1 | AROMATIC SULFONAMIDE DERIVATIVES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2019-04-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190119210-A1 | AROMATIC SULFONAMIDE DERIVATIVES | ARSA, SULT2A1, TPST2 | P2RX4 758/4885ROCK2 4741/4885GSTO1 3638/4885 |
| US-10844016-B2 | Aromatic sulfonamide derivatives | ARSA, SULT2A1, TPST2 | P2RX4 758/4885ROCK2 4741/4885GSTO1 3638/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.