Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GMNN | O75496 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | THPO | P40225 | 1/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25836497 | 0.81 | ALDH1A1 (0.30) | ALDH1A1LMNAPOLBRAB9ASMN1; SMN2 | |
| SCHEMBL28704349 | 0.79 | — | — | |
| SCHEMBL22897401 | 0.79 | KDM4E (0.31) | ALDH1A1KDM4EPLA2G2A | |
| SCHEMBL26781055 | 0.75 | KDM4E (0.30) | ALDH1A1POLBMAPTHTTKDM4E | |
| SCHEMBL26781084 | 0.73 | — | — | |
| SCHEMBL2022996 | 0.72 | APP (0.35) | ALDH1A1LMNAPOLBRAB9ASMN1; SMN2 | |
| SCHEMBL19379579 | 0.70 | ACP1 (0.35) | ALDH1A1LMNAPOLBRAB9ASMN1; SMN2 | |
| SCHEMBL22897394 | 0.70 | ALDH1A1 (0.33) | ALDH1A1LMNAMAPTKDM4ERECQL | |
| SCHEMBL22906079 | 0.70 | ALDH1A1 (0.33) | ALDH1A1LMNAMAPTKDM4ERECQL | |
| SCHEMBL725109 | 0.70 | MAPT (0.33) | MAPTPLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11744916-B2 | Radiopaque polymers | BIOCOMPATIBLES UK LIMITED | 2023-09-05 | — | — | US | disclosed |
| US-11744916-B2 | Radiopaque polymers | BIOCOMPATIBLES UK LIMITED | 2023-09-05 | — | — | US | disclosed |
| US-11702498-B2 | Radiopaque polymers | BIOCOMPATIBLES UK LIMITED | 2023-07-18 | — | — | US | disclosed |
| US-11702498-B2 | Radiopaque polymers | BIOCOMPATIBLES UK LIMITED | 2023-07-18 | — | — | US | disclosed |
| US-20210277162-A1 | RADIOPAQUE POLYMERS | Boston Scientific Medical Device Limited (IE) | 2021-09-09 | — | — | US | disclosed |
| US-20210115171-A1 | RADIOPAQUE POLYMERS | Boston Scientific Medical Device Limited (IE) | 2021-04-22 | — | — | US | disclosed |
| US-20210015963-A1 | RADIOPAQUE POLYMERS | BIOCOMPATIBLES UK LTD. (GB) | 2021-01-21 | — | — | US | disclosed |
| WO-2021009734-A1 | RADIOPAQUE POLYMERS | BIOCOMPATIBLES UK LIMITED (GB) | 2021-01-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210115171-A1 | RADIOPAQUE POLYMERS | C9, PARG, RAD50 | ALDH1A1 4725/4885LMNA 739/4885POLB 1187/4885 |
| US-11702498-B2 | Radiopaque polymers | OXER1, NR5A1, AQP1 | ALDH1A1 3178/4885LMNA 3358/4885POLB 361/4885 |
| US-20210015963-A1 | RADIOPAQUE POLYMERS | TPO, PGLS, IQGAP1 | ALDH1A1 1464/4885LMNA 3452/4885POLB 1066/4885 |
| US-11744916-B2 | Radiopaque polymers | TPO, PGLS, IQGAP1 | ALDH1A1 1464/4885LMNA 3452/4885POLB 1066/4885 |
| US-20210277162-A1 | RADIOPAQUE POLYMERS | OXER1, NR5A1, AQP1 | ALDH1A1 3330/4885LMNA 3337/4885POLB 355/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.