Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 5/20 | 0.57 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.56 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.47 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.47 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.47 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.47 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.47 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29363967 | 1.00 | PTGS2 (0.57) | PTGS2GLASTING1AKR1B1TDP1 | |
| Hydrochloric Acid SCHEMBL49165 | 0.98 | PTGS2 (0.56) | PTGS2GLASTING1AKR1B1TDP1 | |
| Hydrochloric Acid SCHEMBL8900388 | 0.96 | PTGS2 (0.54) | PTGS2GLASTING1AKR1B1TDP1 | |
| Acetic Acid SCHEMBL27649054 | 0.96 | PTGS2 (0.54) | PTGS2GLASTING1AKR1B1TDP1 | |
| Formic Acid SCHEMBL28053598 | 0.91 | PTGS2 (0.50) | PTGS2GLASTING1AKR1B1TDP1 | |
| SCHEMBL19475173 | 0.85 | PTGS2 (0.55) | PTGS2GLASTING1AKR1B1TDP1 | |
| SCHEMBL1258807 | 0.83 | ESR1 (0.43) | PTGS2GLASTING1TDP1SMN1; SMN2 | |
| SCHEMBL7188564 | 0.83 | L3MBTL1 (0.43) | PTGS2GLASTING1SMN1; SMN2KDM4E | |
| SCHEMBL29631318 | 0.83 | AKR1B1 (0.61) | PTGS2AKR1B1TDP1MAPTMEN1 | |
| SCHEMBL2528595 | 0.83 | AKR1B1 (0.61) | PTGS2AKR1B1TDP1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 247 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114591291-A | Bilastine intermediate compound and preparation method thereof | 鲁南制药集团股份有限公司 | 2022-06-07 | — | — | CN | claimed |
| CN-113384702-A | Application of H1 histamine receptor antagonist in preparation of medicine for treating glioma | 温州医科大学附属第一医院 | 2021-09-14 | — | — | CN | claimed |
| CN-111386331-A | Ester compound, lubricating oil composition containing same, and method for producing same | 埃克森美孚化学专利公司 | 2020-07-07 | — | — | CN | claimed |
| EP-1958935-A2 | Process for the production of piperidine derivatives with microorganisms | AMR Technology, Inc. (US) | 2008-08-20 | — | — | EP | claimed |
| US-20060173042-A1 | Process for the preparation of fexofenadine | RANBAXY LABORATORIES LIMITED (IN) | 2006-08-03 | — | — | US | claimed |
| EP-1071463-B1 | METHODS AND COMPOSITIONS USING TERFENADINE METABOLITES IN COMBINATION WITH LEUKOTRIENE INHIBITORS | SEPRACOR INC (US) | 2006-06-07 | — | — | EP | claimed |
| EP-1575893-A1 | PROCESS FOR THE PREPARATION OF FEXOFENADINE | Ranbaxy Laboratories Limited (IN) | 2005-09-21 | — | — | EP | claimed |
| EP-1339864-A4 | PROCESS FOR THE PRODUCTION OF PIPERIDINE DERIVATIVES WITH MICROORGANISMS | AMR TECHNOLOGY INC (US) | 2005-01-12 | — | — | EP | claimed |
| WO-2004054955-A1 | PROCESS FOR THE PREPARATION OF FEXOFENADINE | RANBAXY LABORATORIES LIMITED (US) | 2004-07-01 | — | — | WO | claimed |
| EP-1339864-A2 | PROCESS FOR THE PRODUCTION OF PIPERIDINE DERIVATIVES WITH MICROORGANISMS | Albany Molecular Research, Inc. (US) | 2003-09-03 | — | — | EP | claimed |
| WO-2002083062-A2 | PROCESS FOR THE PRODUCTION OF PIPERIDINE DERIVATIVES WITH MICROORGANISMS | ALBANY MOLECULAR RESEARCH, INC. (US) | 2002-10-24 | — | — | WO | claimed |
| US-20020077482-A1 | Novel intermediates useful for the preparation of antihistaminic piperidine derivatives | MERRELL DOW PHARMACEUTICALS INC. | 2002-06-20 | — | — | US | claimed |
| JP-H08512028-A | — | — | 1996-12-17 | — | — | JP | claimed |
| EP-0705245-A1 | NOVEL INTERMEDIATES FOR THE PREPARATION OF ANTIHISTAMINIC 4-DIPHENYLMETHYL/DIPHENYLMETHOXY PIPERIDINE DERIVATIVES | MERRELL PHARMACEUTICALS INC. (US) | 1996-04-10 | — | — | EP | claimed |
| WO-1995000480-A1 | NOVEL INTERMEDIATES FOR THE PREPARATION OF ANTIHISTAMINIC 4-DIPHENYLMETHYL/DIPHENYLMETHOXY PIPERIDINE DERIVATIVES | MERRELL PHARMACEUTICALS INC. (US) | 1995-01-05 | — | — | WO | claimed |
| US-4393233-A | FROM ISOBUTYRIC ACID, BROMINE, AND BENZENE | ALLIED CORPORATION (US) | 1983-07-12 | — | — | US | claimed |
| US-4310655-A | Polymers of p-(1,1-dimethyl-2-hydroxyethyl)benzoic acid and preparation thereof | ALLIED CORPORATION (US) | 1982-01-12 | — | — | US | claimed |
| JP-59073505-A | — | — | None | — | — | JP | disclosed |
| US-4254129-A | ANTIALLERGENS, BRONCHODILATORS, ANTIHISTAMINES; 4-DIPHENYLMETHYL PIPERIDINO-ALKANOLS | RICHARDSON-MERRELL INC. (US) | 1981-03-03 | — | — | US | disclosed |
| US-4204029-A | AUTOMOBILE WINDSHIELDS | GULF OIL CORPORATION (US) | 1980-05-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020077482-A1 | Novel intermediates useful for the preparation of antihistaminic piperidine derivatives | HRH1, HRH3, HRH4 | PTGS2 301/4885GLA 4650/4885STING1 1344/4885 |
| US-20060173042-A1 | Process for the preparation of fexofenadine | CMA1, HRH2, MAOA | PTGS2 469/4885GLA 2774/4885STING1 4664/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.