Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL228994 | 0.83 | PTGS2 (0.57) | ESR1ESR2GLASTING1PTGS2 | |
| SCHEMBL29363967 | 0.83 | PTGS2 (0.57) | ESR1ESR2GLASTING1PTGS2 | |
| SCHEMBL7188564 | 0.83 | L3MBTL1 (0.43) | ESR1ESR2P2RX7GLASTING1 | |
| SCHEMBL1259145 | 0.83 | CTBP2 (0.56) | PTGS2CTBP2MAPTMEN1KMT2A | |
| SCHEMBL7405623 | 0.82 | P2RX7 (0.44) | ESR1ESR2P2RX7GLASTING1 | |
| Hydrochloric Acid SCHEMBL49165 | 0.82 | PTGS2 (0.56) | ESR1ESR2GLASTING1PTGS2 | |
| SCHEMBL339508 | 0.82 | P2RX7 (0.44) | ESR1ESR2P2RX7GLASTING1 | |
| SCHEMBL1257814 | 0.81 | SMN1; SMN2 (0.39) | GLASTING1CTBP2MAPTMEN1 | |
| Hydrochloric Acid SCHEMBL14167164 | 0.80 | P2RX7 (0.43) | ESR1ESR2P2RX7GLASTING1 | |
| Hydrochloric Acid SCHEMBL8900388 | 0.80 | PTGS2 (0.54) | ESR1ESR2GLASTING1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120142988-A1 | METHOD OF PRODUCING 1-HEXENE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-06-07 | — | — | US | disclosed |
| WO-2011016581-A1 | METHOD OF PRODUCING 1-HEXENE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-02-10 | — | — | WO | disclosed |
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120142988-A1 | METHOD OF PRODUCING 1-HEXENE | HRH1, HK1, HMOX1 | ESR1 970/4885ESR2 866/4885P2RX7 2883/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.