SCHEMBL7188564

SCHEMBL7188564

CC(=O)Cc1cccc(C)c1C

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.43
ESR1 P03372 1/20 0.43
ESR2 Q92731 1/20 0.43
P2RX7 Q99572 1/20 0.42
PPARG P37231 1/20 0.42
GLA P06280 1/20 0.42
STING1 Q86WV6 1/20 0.42
TRPA1 O75762 1/20 0.41
ATM Q13315 1/20 0.41
PTGS2 P35354 2/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
CTBP2 P56545 1/20 0.41
CD38 P28907 1/20 0.40
MAPT P10636 2/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
KDM4C Q9H3R0 1/20 0.40
KDM4E B2RXH2 1/20 0.40
LMNA P02545 1/20 0.40
POLB P06746 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28561770 0.91 L3MBTL1 (0.38) L3MBTL1ESR1ESR2P2RX7PPARG
Acetic Acid SCHEMBL27649054 0.84 PTGS2 (0.54) ESR1ESR2GLASTING1PTGS2
SCHEMBL1258807 0.83 ESR1 (0.43) L3MBTL1ESR1ESR2P2RX7PPARG
SCHEMBL29363967 0.83 PTGS2 (0.57) ESR1ESR2GLASTING1PTGS2
SCHEMBL228994 0.83 PTGS2 (0.57) ESR1ESR2GLASTING1PTGS2
SCHEMBL30446395 0.83 CTBP2 (0.56) L3MBTL1PTGS2SMN1; SMN2CTBP2MAPT
SCHEMBL782187 0.83 CTBP2 (0.56) L3MBTL1PTGS2SMN1; SMN2CTBP2MAPT
SCHEMBL2545614 0.82 IAPP (0.50) L3MBTL1TRPA1ATMMAPTMEN1
SCHEMBL7405623 0.82 P2RX7 (0.44) L3MBTL1ESR1ESR2P2RX7PPARG
SCHEMBL5991730 0.82 ALDH1A1 (0.50) L3MBTL1TRPA1PTGS2SMN1; SMN2CTBP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117447638-B Vinegar-modified resin and preparation method and application thereof 珠海市铠信科技有限公司 2024-07-26 CN disclosed
CN-117447638-A Vinegar-modified resin and preparation method and application thereof 珠海市铠信科技有限公司 2024-01-26 CN disclosed
CN-113004341-A PNO ligand containing chiral ferrocene and axial chiral biphenol and application thereof 洛阳师范学院 2021-06-22 CN disclosed
US-10441946-B2 Linear alpha-olefin catalysts and preparation and use thereof APALENE TECHNOLOGY CO., LTD. (HANGZHOU) (CN) 2019-10-15 US disclosed
US-20180147571-A1 NOVEL LINEAR ALPHA-OLEFIN CATALYSTS AND PREPARATION AND USE THEREOF APALENE TECHNOLOGY CO., LTD. (JIAXING) (CN) 2018-05-31 US disclosed
EP-1307423-A1 NEW PROCESSES FOR THE PRODUCTION OF FEXOFENADINE Texcontor Etablissement (LI) 2003-05-07 EP disclosed
WO-2002010115-A1 NEW PROCESSES FOR THE PRODUCTION OF FEXOFENADINE TEXCONTOR ETABLISSEMENT (LI) 2002-02-07 WO disclosed
EP-0200942-A2 New derivatives of an aminoketone NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1986-11-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180147571-A1 NOVEL LINEAR ALPHA-OLEFIN CATALYSTS AND PREPARATION AND USE THEREOF UBE2L3, RNF168, AGL L3MBTL1 104/4885ESR1 30/4885ESR2 60/4885
US-10441946-B2 Linear alpha-olefin catalysts and preparation and use thereof UBE2L3, COG8, ACSL3 L3MBTL1 96/4885ESR1 43/4885ESR2 84/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.