SCHEMBL2289971

SCHEMBL2289971

COC(C)(C)c1ccc(CO)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARG P37231 1/20 0.43
PPARA Q07869 1/20 0.43
RORC P51449 1/20 0.42
EPHX2 P34913 2/20 0.42
LTA4H P09960 1/20 0.38
TSHR P16473 1/20 0.37
ESR1 P03372 2/20 0.36
ESR2 Q92731 2/20 0.36
KIF11 P52732 1/20 0.36
ALDH1A1 P00352 1/20 0.35
ALOX15 P16050 1/20 0.35
NOS3 P29474 1/20 0.35
NOS1 P29475 1/20 0.35
ERN1 O75460 1/20 0.35
PRSS1 P07477 1/20 0.34
PRSS2 P07478 1/20 0.34
PRSS3 P35030 1/20 0.34
KLF10 Q13118 1/20 0.34
CA1 P00915 2/20 0.33
CA2 P00918 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL43313 0.81 MAPK1 (0.46) RORCEPHX2TSHRESR1ESR2
SCHEMBL17320466 0.80 RORC (0.43) RORCTSHRESR1ESR2KIF11
SCHEMBL9694556 0.78 RORC (0.39) RORCTSHRESR1ESR2ALDH1A1
SCHEMBL10357375 0.78 RORC (0.39) RORCESR1ESR2ERN1MAPK1
SCHEMBL1237460 0.78 LOXL2 (0.42) RORCKIF11NOS3NOS1
SCHEMBL10454154 0.77 TP53 (0.38) RORCTSHRALDH1A1ALOX15
SCHEMBL18911101 0.77 RORC (0.41) RORCALDH1A1CA2MEN1KMT2A
SCHEMBL113722 0.77 EPHX2 (0.61) PPARGPPARAEPHX2TSHRNR1H4
SCHEMBL787308 0.77 ESR1 (0.52) PPARGPPARAEPHX2LTA4HTSHR
Methoxymethane SCHEMBL28431429 0.75 TSHR (0.53) PPARGPPARALTA4HTSHRNOS3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2534281-B1 METHOD FOR PRODUCING 4-ISOPROPYLCYCLOHEXYLMETHANOL BASF SE (DE) 2019-01-09 EP claimed
US-8889920-B2 Process for preparing 4-isopropylcyclohexylmethanol BASF SE (DE) 2014-11-18 US claimed
US-20110207968-A1 PROCESS FOR PREPARING 4-ISOPROPYLCYCLOHEXYLMETHANOL BASF SE (DE) 2011-08-25 US claimed
EP-2534281-B1 METHOD FOR PRODUCING 4-ISOPROPYLCYCLOHEXYLMETHANOL BASF SE (DE) 2019-01-09 EP disclosed
US-8889920-B2 Process for preparing 4-isopropylcyclohexylmethanol BASF SE (DE) 2014-11-18 US disclosed
EP-2534281-A2 METHOD FOR PRODUCING 4-ISOPROPYLCYCLOHEXYLMETHANOL BASF SE (DE) 2012-12-19 EP disclosed
US-20110207968-A1 PROCESS FOR PREPARING 4-ISOPROPYLCYCLOHEXYLMETHANOL BASF SE (DE) 2011-08-25 US disclosed
WO-2011098432-A2 METHOD FOR PRODUCING 4-ISOPROPYLCYCLOHEXYLMETHANOL BASF SE (DE) 2011-08-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110207968-A1 PROCESS FOR PREPARING 4-ISOPROPYLCYCLOHEXYLMETHANOL CYP2E1, CYP3A4, DHPS PPARG 3288/4885PPARA 2772/4885RORC 4185/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.