SCHEMBL22901112

SCHEMBL22901112

c1ccc(-c2nc3ccccc3nc2-c2ccc(-c3ccc4c(ccc5c6ccccc6oc45)c3)c3ccccc23)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.40
L3MBTL1 Q9Y468 6/20 0.39
KMT2A Q03164 3/20 0.39
MEN1 O00255 2/20 0.39
MAPT P10636 2/20 0.39
CSF1R P07333 1/20 0.39
PDGFRB P09619 1/20 0.39
KIT P10721 1/20 0.39
FLT3 P36888 1/20 0.39
HDAC6 Q9UBN7 1/20 0.39
KDM4E B2RXH2 6/20 0.38
LMNA P02545 4/20 0.38
GAA P10253 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
ALDH1A1 P00352 5/20 0.36
NPSR1 Q6W5P4 1/20 0.36
THRB P10828 1/20 0.36
CYP1A1 P04798 3/20 0.35
CYP1B1 Q16678 3/20 0.35
CYP1A2 P05177 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22880066 0.91 KDM4E (0.43) ALOX5L3MBTL1KMT2AMEN1MAPT
SCHEMBL22880525 0.90 L3MBTL1 (0.42) ALOX5L3MBTL1KMT2AMEN1MAPT
SCHEMBL24363630 0.89 CYP1A1 (0.36) ALOX5KMT2AMEN1MAPTCSF1R
SCHEMBL22880243 0.86 L3MBTL1 (0.49) ALOX5L3MBTL1KMT2AMEN1MAPT
SCHEMBL22880117 0.84 ALOX5 (0.33) ALOX5L3MBTL1KMT2AMEN1MAPT
SCHEMBL24275448 0.84 L3MBTL1 (0.39) ALOX5L3MBTL1KMT2AMEN1MAPT
SCHEMBL22879847 0.84 KDM4E (0.43) ALOX5L3MBTL1KMT2AMEN1MAPT
SCHEMBL24275044 0.83 L3MBTL1 (0.39) ALOX5L3MBTL1KMT2AMEN1MAPT
SCHEMBL24274988 0.82 L3MBTL1 (0.39) ALOX5L3MBTL1KMT2AMEN1MAPT
SCHEMBL22880367 0.81 ALOX5 (0.42) ALOX5KMT2AMEN1MAPTCSF1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230345827-A1 PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2023-10-26 US disclosed
US-20230345827-A1 PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2023-10-26 US disclosed
US-11793075-B2 Plurality of host materials and organic electroluminescent device comprising the same ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. 2023-10-17 US disclosed
US-11793075-B2 Plurality of host materials and organic electroluminescent device comprising the same ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. 2023-10-17 US disclosed
US-20230126428-A1 PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2023-04-27 US disclosed
US-20230126428-A1 PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2023-04-27 US disclosed
US-11552257-B2 Plurality of host materials and organic electroluminescent device comprising the same ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. 2023-01-10 US disclosed
US-20220131081-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2022-04-28 US disclosed
US-20210028373-A1 A PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2021-01-28 US disclosed
US-20210020849-A1 PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2021-01-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210028373-A1 A PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME TERT, TELO2, LIMS1 ALOX5 956/4885L3MBTL1 46/4885KMT2A 2746/4885
US-20220131081-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME LEF1, ODC1, TMEM109 ALOX5 336/4885L3MBTL1 633/4885KMT2A 2186/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.