SCHEMBL229015

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL20821058	0.83	POLB (0.54)	POLBESR1ESR2CYP19A1L3MBTL1
	SCHEMBL224658	0.83	LTA4H (0.47)	ESR1ESR2CYP19A1L3MBTL1CALM1
	SCHEMBL18879236	0.77	ALDH1A1 (0.40)	L3MBTL1NPC1RAB9AMAPTALDH1A1
	SCHEMBL27813299	0.77	ESR1 (0.76)	ESR1ESR2CYP19A1L3MBTL1CALM1
	SCHEMBL51705	0.75	POLB (0.61)	POLBESR1ESR2CYP19A1L3MBTL1
	SCHEMBL24383957	0.73	ESR1 (0.59)	ESR1ESR2L3MBTL1NPC1RAB9A
	SCHEMBL135264	0.73	POLB (0.59)	POLBESR1ESR2CYP19A1L3MBTL1
	SCHEMBL2045876	0.73	POLB (0.64)	POLBESR1ESR2CYP19A1L3MBTL1
	SCHEMBL1506598	0.73	CA1 (0.50)	L3MBTL1NPC1RAB9AMAPTALDH1A1
	SCHEMBL227700	0.73	ESR1 (0.61)	POLBESR1ESR2CYP19A1CALM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.