Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 3/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | RPLP1 | P05386 | 2/20 | 0.33 |
| ▸ | RPLP0 | P05388 | 2/20 | 0.33 |
| ▸ | RPS17 | P08708 | 2/20 | 0.33 |
| ▸ | RPSA | P08865 | 2/20 | 0.33 |
| ▸ | RPS2 | P15880 | 2/20 | 0.33 |
| ▸ | RPL35A | P18077 | 2/20 | 0.33 |
| ▸ | RPL7 | P18124 | 2/20 | 0.33 |
| ▸ | RPL17 | P18621 | 2/20 | 0.33 |
| ▸ | RPS4Y1 | P22090 | 2/20 | 0.33 |
| ▸ | RPS3 | P23396 | 2/20 | 0.33 |
| ▸ | RPS12 | P25398 | 2/20 | 0.33 |
| ▸ | RPL13 | P26373 | 2/20 | 0.33 |
| ▸ | RPL10 | P27635 | 2/20 | 0.33 |
| ▸ | RPL12 | P30050 | 2/20 | 0.33 |
| ▸ | RPL9; RPL9P7; RPL9P8; RPL9P9 | P32969 | 2/20 | 0.33 |
| ▸ | RPL22 | P35268 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22902468 | 0.86 | L3MBTL1 (0.39) | OPRM1GRIN1GRIN2BHRH1HRH4 | |
| SCHEMBL29737046 | 0.82 | SLC2A1 (0.36) | OPRM1KCNH2SMN1; SMN2HRH1HRH4 | |
| SCHEMBL31280171 | 0.82 | SLC2A1 (0.35) | OPRM1KCNH2CHRM2CHRM1CHRM3 | |
| SCHEMBL32664297 | 0.82 | SLC2A1 (0.35) | OPRM1KCNH2CHRM2CHRM1CHRM3 | |
| SCHEMBL31279004 | 0.81 | SLC2A1 (0.35) | OPRM1SMN1; SMN2HRH1HRH4LMNA | |
| SCHEMBL32664570 | 0.81 | SLC2A1 (0.35) | OPRM1SMN1; SMN2HRH1HRH4LMNA | |
| SCHEMBL18289976 | 0.81 | HTR6 (0.40) | OPRM1HRH1HRH4ALDH1A1 | |
| SCHEMBL30111801 | 0.81 | HTR6 (0.40) | OPRM1HRH1HRH4ALDH1A1 | |
| SCHEMBL29471042 | 0.80 | OPRM1 (0.46) | OPRM1KCNH2RPLP1RPLP0RPS17 | |
| SCHEMBL22902495 | 0.79 | PIK3R1 (0.38) | BUB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021011428-A1 | HETEROCYCLIC KINASE INHIBITORS | GB005, INC. (US) | 2021-01-21 | — | — | WO | disclosed |