Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | CASP3 | P42574 | 2/20 | 0.54 |
| ▸ | TDP2 | O95551 | 5/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.44 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | CASP9 | P55211 | 1/20 | 0.42 |
| ▸ | CASP6 | P55212 | 1/20 | 0.42 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.42 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.42 |
| ▸ | AHR | P35869 | 1/20 | 0.42 |
| ▸ | CCNE2 | O96020 | 3/20 | 0.41 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3659895 | 0.82 | AHR (0.50) | ALDH1A1HPGDKDM4EGAAHSD17B10 | |
| SCHEMBL22904498 | 0.82 | CASP3 (0.56) | ALDH1A1HPGDKDM4EHSD17B10CASP3 | |
| SCHEMBL22904503 | 0.81 | TDP2 (0.58) | ALDH1A1HPGDKDM4EGAAHSD17B10 | |
| SCHEMBL24632112 | 0.79 | ALDH1A1 (0.55) | ALDH1A1HPGDKDM4EGAAHSD17B10 | |
| SCHEMBL22904358 | 0.78 | TDP2 (0.54) | ALDH1A1HPGDKDM4EGAAHSD17B10 | |
| SCHEMBL22904353 | 0.77 | TDP2 (0.53) | ALDH1A1HPGDKDM4EHSD17B10CASP3 | |
| SCHEMBL7960619 | 0.75 | KDM4E (1.00) | ALDH1A1HPGDKDM4EGAAHSD17B10 | |
| SCHEMBL22904526 | 0.75 | TDP2 (0.54) | ALDH1A1HPGDKDM4EGAACASP3 | |
| SCHEMBL1273609 | 0.74 | NPC1 (0.68) | ALDH1A1HPGDKDM4EGAAHSD17B10 | |
| SCHEMBL30002207 | 0.74 | NPC1 (0.68) | ALDH1A1HPGDKDM4EGAAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021011631-A1 | FUSED-GLUTARIMIDE CRBN LIGANDS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2021-01-21 | — | — | WO | disclosed |