SCHEMBL22908237

SCHEMBL22908237

c1ccc(-c2ccc(-c3nc(-c4ccccc4)nc(-c4cccc5c4-c4ccccc4C54c5ccccc5Sc5c(-c6ccc(-c7nc(-c8ccccc8)nc(-c8cccc9c8-c8ccccc8C98c9ccccc9Sc9ccccc98)n7)cc6)cccc54)n3)cc2)cc1

nearest known ligand 0.31

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ADORA3 P0DMS8 1/20 0.31
ALOX15 P16050 1/20 0.31
TSHR P16473 1/20 0.31
ADORA2A P29274 1/20 0.31
ADORA2B P29275 1/20 0.31
ADORA1 P30542 1/20 0.31
GPR55 Q9Y2T6 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21151252 0.93 ALOX15 (0.35) ADORA3ALOX15TSHRADORA2AADORA2B
SCHEMBL22908169 0.93 ALOX15 (0.35) ADORA3ALOX15TSHRADORA2AADORA2B
SCHEMBL21477886 0.92 ALOX15 (0.34) ADORA3ALOX15TSHRADORA2AADORA2B
SCHEMBL22908146 0.92 MEN1 (0.34) ADORA2AADORA1
SCHEMBL23257141 0.91 ABCG2 (0.34)
SCHEMBL21343160 0.91 ABCG2 (0.34)
SCHEMBL23814391 0.91 ADORA3 (0.33) ADORA3ALOX15TSHRADORA2AADORA2B
SCHEMBL23814866 0.91 ADORA3 (0.33) ADORA3ALOX15TSHRADORA2AADORA2B
SCHEMBL23814913 0.91 L3MBTL1 (0.33) ADORA3ALOX15TSHRADORA2AADORA2B
SCHEMBL21658271 0.91 L3MBTL1 (0.33) ADORA3ALOX15TSHRADORA2AADORA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210020842-A1 ORGANIC LIGHT-EMITTING DEVICE LG CHEM, LTD. (KR) 2021-01-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210020842-A1 ORGANIC LIGHT-EMITTING DEVICE OR10J3, OR51E2, LOXL1 ADORA3 4367/4885ALOX15 373/4885TSHR 2461/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.