SCHEMBL21151252

SCHEMBL21151252

c1ccc(-c2ccc(-c3nc(-c4ccccc4)nc(-c4cccc5c4-c4ccccc4C54c5ccccc5Sc5ccccc54)n3)cc2)cc1

nearest known ligand 0.35

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 2/20 0.35
TSHR P16473 2/20 0.35
ADORA3 P0DMS8 1/20 0.35
ADORA2A P29274 1/20 0.35
ADORA2B P29275 1/20 0.35
ADORA1 P30542 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.33
MEN1 O00255 2/20 0.32
ALDH1A1 P00352 2/20 0.32
MAPT P10636 2/20 0.32
HPGD P15428 2/20 0.32
KMT2A Q03164 2/20 0.32
LMNA P02545 2/20 0.31
KDM4E B2RXH2 1/20 0.31
GLA P06280 1/20 0.31
GPR55 Q9Y2T6 1/20 0.31
PDK2 Q15119 3/20 0.30
GAA P10253 1/20 0.30
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22908169 1.00 ALOX15 (0.35) ALOX15TSHRADORA3ADORA2AADORA2B
SCHEMBL21477886 0.99 ALOX15 (0.34) ALOX15TSHRADORA3ADORA2AADORA2B
SCHEMBL21151976 0.97 TSHR (0.36) ALOX15TSHRADORA3ADORA2AADORA2B
SCHEMBL22908045 0.95 ADORA3 (0.35) ALOX15TSHRADORA3ADORA2AADORA2B
SCHEMBL22074232 0.94 ADORA3 (0.33) ALOX15TSHRADORA3ADORA2AADORA2B
SCHEMBL21151247 0.93 ADORA3 (0.35) ALOX15TSHRADORA3ADORA2AADORA2B
SCHEMBL22908237 0.93 ADORA3 (0.31) ALOX15TSHRADORA3ADORA2AADORA2B
SCHEMBL23565741 0.92 MEN1 (0.38) ADORA2AADORA1MEN1ALDH1A1MAPT
SCHEMBL23965323 0.92 MEN1 (0.35) ALOX15TSHRADORA3ADORA2AADORA2B
SCHEMBL24844555 0.91 MEN1 (0.33) ALOX15TSHRADORA3ADORA2AADORA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024117762-A1 ORGANIC LIGHT EMITTING DEVICE 주식회사 엘지화학 2024-06-06 WO disclosed
US-20230006161-A1 ORGANIC LIGHT-EMITTING DEVICE LG CHEM, LTD. (KR) 2023-01-05 US disclosed
US-20210143344-A1 ORGANIC LIGHT-EMITTING DEVICE LG CHEM, LTD. (KR) 2021-05-13 US disclosed
US-20210020842-A1 ORGANIC LIGHT-EMITTING DEVICE LG CHEM, LTD. (KR) 2021-01-21 US disclosed
WO-2020022768-A1 ORGANIC LIGHT EMITTING DIODE 주식회사 엘지화학 2020-01-30 WO disclosed
WO-2020022771-A1 ORGANIC LIGHT-EMITTING DEVICE 주식회사 엘지화학 2020-01-30 WO disclosed
US-20190214571-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2019-07-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190214571-A1 ORGANIC LIGHT EMITTING DEVICE PPOX, ERO1A, HMOX2 ALOX15 151/4885TSHR 1754/4885ADORA3 4692/4885
US-20210020842-A1 ORGANIC LIGHT-EMITTING DEVICE OR10J3, OR51E2, LOXL1 ALOX15 373/4885TSHR 2461/4885ADORA3 4367/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.