Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 4/20 | 0.38 |
| ▸ | DRD2 | P14416 | 3/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.36 |
| ▸ | CCR8 | P51685 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22908538 | 0.88 | CCR8 (0.41) | LMNAHTR1ADRD2ADRA1AALDH1A1 | |
| SCHEMBL22992174 | 0.85 | HTT (0.41) | L3MBTL1LMNAALDH1A1KDM4EKMT2A | |
| SCHEMBL22908539 | 0.84 | CCR8 (0.47) | L3MBTL1DRD2ADRA1APDE4BALDH1A1 | |
| SCHEMBL22908536 | 0.84 | CYP2D6 (0.37) | KMT2ATSHRMAPT | |
| SCHEMBL22908552 | 0.84 | CYP3A4 (0.44) | LMNAALDH1A1SMN1; SMN2KMT2ACCR8 | |
| SCHEMBL22908431 | 0.84 | GRM3 (0.46) | L3MBTL1HTR1AALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL22908437 | 0.83 | MGLL (0.44) | L3MBTL1LMNAHTR1ADRD2ALDH1A1 | |
| SCHEMBL22908423 | 0.83 | BTK (0.31) | KDM4EKMT2AMAPT | |
| SCHEMBL22908447 | 0.82 | HTR4 (0.34) | PDE4BCCR8KCNH2 | |
| SCHEMBL22908541 | 0.82 | LMNA (0.38) | LMNAALDH1A1SMN1; SMN2KMT2AMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021009048-A1 | HERBICIDAL CYCLOHEXANEDIONE DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2021-01-21 | — | — | WO | disclosed |