Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK1 | P23458 | 8/20 | 0.35 |
| ▸ | JAK2 | O60674 | 7/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 4/20 | 0.33 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.32 |
| ▸ | CDK9 | P50750 | 2/20 | 0.32 |
| ▸ | TYK2 | P29597 | 2/20 | 0.32 |
| ▸ | JAK3 | P52333 | 2/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | MAP3K19 | Q56UN5 | 1/20 | 0.32 |
| ▸ | BMP2K | Q9NSY1 | 1/20 | 0.32 |
| ▸ | GHSR | Q92847 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22908426 | 0.93 | JAK1 (0.37) | JAK1JAK2IRAK4TYK2JAK3 | |
| SCHEMBL24120375 | 0.91 | PDCD1LG2 (0.36) | JAK1JAK2IRAK4CCNT1CDK9 | |
| SCHEMBL22992131 | 0.90 | IRAK4 (0.33) | JAK1JAK2IRAK4CCNT1CDK9 | |
| SCHEMBL22908540 | 0.89 | CYP2D6 (0.41) | MAPK1 | |
| SCHEMBL22908536 | 0.87 | CYP2D6 (0.37) | — | |
| SCHEMBL22908425 | 0.86 | CCR1 (0.32) | KCNH2ADAMTS5GHSR | |
| SCHEMBL22908435 | 0.85 | GHSR (0.33) | ADAMTS5MAPK1GHSR | |
| SCHEMBL22908447 | 0.84 | HTR4 (0.34) | KCNH2 | |
| SCHEMBL22908541 | 0.84 | LMNA (0.38) | — | |
| SCHEMBL22908427 | 0.84 | HTR4 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021009048-A1 | HERBICIDAL CYCLOHEXANEDIONE DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2021-01-21 | — | — | WO | disclosed |