Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 4/20 | 0.33 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22908540 | 0.90 | CYP2D6 (0.41) | CYP2D6CYP2C19CYP3A4MEN1KMT2A | |
| SCHEMBL22908408 | 0.89 | GHSR (0.33) | GHSRCYP2D6CYP2C19GAAMEN1 | |
| SCHEMBL21344852 | 0.86 | BDKRB1 (0.32) | BTKCYP2D6MAPK1ALDH1A1CYP1A2 | |
| SCHEMBL22908424 | 0.85 | JAK1 (0.35) | GHSRADAMTS5MAPK1 | |
| SCHEMBL22908536 | 0.85 | CYP2D6 (0.37) | BTKCYP2D6MEN1KMT2ACYP1A2 | |
| SCHEMBL22908425 | 0.84 | CCR1 (0.32) | GHSRCYP2C19CYP3A4GAAADAMTS5 | |
| SCHEMBL22908427 | 0.82 | HTR4 (0.34) | BTKCYP3A4ALDH1A1 | |
| SCHEMBL22908541 | 0.82 | LMNA (0.38) | GAAMEN1KMT2AALDH1A1TSHR | |
| SCHEMBL22908447 | 0.82 | HTR4 (0.34) | BTK | |
| SCHEMBL22908423 | 0.81 | BTK (0.31) | BTKMEN1KMT2AADAMTS5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021009048-A1 | HERBICIDAL CYCLOHEXANEDIONE DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2021-01-21 | — | — | WO | disclosed |