Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | KCNK3 | O14649 | 5/20 | 0.35 |
| ▸ | KCNK9 | Q9NPC2 | 5/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.34 |
| ▸ | CCR8 | P51685 | 3/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.34 |
| ▸ | ACACA | Q13085 | 1/20 | 0.34 |
| ▸ | MAP3K14 | Q99558 | 2/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22908445 | 0.89 | CYP3A4 (0.34) | HTR1ACCR8KCNH2ACACAMAP3K14 | |
| SCHEMBL22908554 | 0.88 | IRAK4 (0.37) | CCR8KCNH2ACACAIRAK4 | |
| SCHEMBL21344262 | 0.88 | KCNK3 (0.36) | HTR1AKCNK3KCNK9EPHX2CCR8 | |
| SCHEMBL22908539 | 0.88 | CCR8 (0.47) | CCR8KCNH2 | |
| SCHEMBL22908555 | 0.87 | CCR8 (0.36) | HTR1ACCR8KCNH2ACACA | |
| SCHEMBL22908538 | 0.85 | CCR8 (0.41) | HTR1ACCR8KCNH2 | |
| SCHEMBL22908432 | 0.85 | ACACA (0.33) | CCR8KCNH2ACACA | |
| SCHEMBL22908552 | 0.84 | CYP3A4 (0.44) | CCR8KCNH2 | |
| SCHEMBL22908441 | 0.84 | DRD3 (0.41) | HTR1AHRH3CCR8KCNH2 | |
| SCHEMBL22908440 | 0.84 | HTR1A (0.37) | HTR1ACCR8KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021009048-A1 | HERBICIDAL CYCLOHEXANEDIONE DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2021-01-21 | — | — | WO | disclosed |