Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 4/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CHKA | P35790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22909374 | 0.84 | TAAR1 (0.39) | AOC3SIGMAR1TAAR1ALDH1A1TSHR | |
| SCHEMBL22909268 | 0.82 | ALDH1A1 (0.41) | ALDH1A1CYP3A4 | |
| SCHEMBL22909452 | 0.81 | CYP2A6 (0.38) | MAOBMAOACYP19A1TSHR | |
| SCHEMBL22909382 | 0.76 | SIGMAR1 (0.40) | AOC3SIGMAR1TAAR1 | |
| SCHEMBL22909610 | 0.74 | CA12 (0.39) | — | |
| SCHEMBL22909581 | 0.71 | DAO (0.37) | MAOBALDH1A1 | |
| SCHEMBL22909469 | 0.70 | ALDH1A1 (0.37) | AOC3TAAR1ALDH1A1TSHR | |
| SCHEMBL22909632 | 0.66 | CA12 (0.43) | MAOBMAOAAOC3TAAR1ALDH1A1 | |
| SCHEMBL3482833 | 0.65 | GFER (1.00) | GFERMAOBMAOACYP19A1ALDH1A1 | |
| SCHEMBL187043 | 0.65 | GFER (1.00) | GFERMAOBMAOACYP19A1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021009568-A1 | BENZENESULFONAMIDE DERIVATIVES AND USES THEREOF | 2692372 ONTARIO, INC. (CA) | 2021-01-21 | — | — | WO | disclosed |