SCHEMBL22909281

SCHEMBL22909281

Cc1ccc(-c2c(F)c(F)c(F)c(F)c2SN(C)C)cc1

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 2/20 0.33
ACHE P22303 1/20 0.32
PTGS1 P23219 1/20 0.32
ALDH1A1 P00352 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22909384 0.84 TYMP (0.33) ACHE
SCHEMBL22909257 0.81 KIF11 (0.36) ACHE
SCHEMBL22909496 0.81 LMNA (0.33)
SCHEMBL4155727 0.76 ACHE (0.48) PTGS2ACHEPTGS1ALDH1A1
SCHEMBL13170620 0.74 ACHE (0.46) PTGS2ACHEPTGS1
SCHEMBL4152903 0.74 ACHE (0.46) PTGS2ACHEPTGS1ALDH1A1
SCHEMBL4147252 0.73 ACHE (0.50) PTGS2ACHEPTGS1ALDH1A1
SCHEMBL1673093 0.70 ACHE (0.42) PTGS2ACHEPTGS1
SCHEMBL27457077 0.69 ACHE (0.40) PTGS2ACHEPTGS1
SCHEMBL3964861 0.68 ACHE (0.43) PTGS2ACHEPTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021009568-A1 BENZENESULFONAMIDE DERIVATIVES AND USES THEREOF 2692372 ONTARIO, INC. (CA) 2021-01-21 WO disclosed