SCHEMBL22909496

SCHEMBL22909496

CCc1ccc(-c2c(F)c(F)c(F)c(F)c2SN(C)C)cc1

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.33
NISCH Q9Y2I1 1/20 0.32
EGFR P00533 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22909281 0.81 PTGS2 (0.33)
SCHEMBL22909384 0.80 TYMP (0.33) LMNA
SCHEMBL22909600 0.79 IDO1 (0.36) LMNA
SCHEMBL12835528 0.78 LMNA (0.43) LMNANISCHEGFR
SCHEMBL22909257 0.77 KIF11 (0.36) NISCH
SCHEMBL22909449 0.72 HDAC3 (0.34) LMNA
SCHEMBL26188086 0.71 CYP2A6 (0.39) LMNAEGFR
SCHEMBL26188101 0.70 CYP2A6 (0.38) LMNAEGFR
SCHEMBL19182654 0.68 LMNA (0.38) LMNANISCHEGFR
SCHEMBL22909164 0.66 CA12 (0.49) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021009568-A1 BENZENESULFONAMIDE DERIVATIVES AND USES THEREOF 2692372 ONTARIO, INC. (CA) 2021-01-21 WO disclosed