Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22909281 | 0.84 | PTGS2 (0.33) | ACHE | |
| SCHEMBL22909496 | 0.80 | LMNA (0.33) | LMNA | |
| SCHEMBL22909257 | 0.80 | KIF11 (0.36) | ACHE | |
| SCHEMBL28361400 | 0.76 | TYMP (0.37) | TYMPLMNAMAPTHTT | |
| SCHEMBL7713106 | 0.72 | LMNA (0.48) | TYMPLMNAMAPTHTTACHE | |
| SCHEMBL247368 | 0.72 | LMNA (0.48) | TYMPLMNAMAPTHTTACHE | |
| SCHEMBL22909164 | 0.70 | CA12 (0.49) | LMNAMAPTHTT | |
| SCHEMBL22909469 | 0.70 | ALDH1A1 (0.37) | — | |
| SCHEMBL7704707 | 0.70 | LMNA (0.46) | TYMPLMNAMAPTHTTACHE | |
| SCHEMBL6402127 | 0.70 | LMNA (0.46) | TYMPLMNAMAPTHTTACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021009568-A1 | BENZENESULFONAMIDE DERIVATIVES AND USES THEREOF | 2692372 ONTARIO, INC. (CA) | 2021-01-21 | — | — | WO | disclosed |