Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | CD274 | Q9NZQ7 | 6/20 | 0.48 |
| ▸ | PDCD1 | Q15116 | 4/20 | 0.48 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MIF | P14174 | 2/20 | 0.35 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22908674 | 0.86 | KMT2A (0.70) | KMT2AMAPTMEN1LMNACD274 | |
| SCHEMBL10435326 | 0.78 | MAPT (0.75) | KMT2AMAPTMEN1LMNACD274 | |
| SCHEMBL22908646 | 0.76 | KMT2A (0.61) | KMT2AMAPTMEN1LMNACD274 | |
| SCHEMBL22908712 | 0.75 | KMT2A (0.60) | KMT2AMAPTMEN1LMNACD274 | |
| SCHEMBL7399166 | 0.74 | PDCD1 (0.53) | KMT2AMAPTMEN1LMNACD274 | |
| SCHEMBL22909489 | 0.73 | CD274 (0.57) | KMT2AMAPTMEN1LMNACD274 | |
| SCHEMBL22908683 | 0.71 | KMT2A (0.58) | KMT2AMAPTMEN1LMNACD274 | |
| SCHEMBL9770297 | 0.70 | MAPT (0.60) | KMT2AMAPTMEN1LMNACD274 | |
| SCHEMBL22909301 | 0.69 | KMT2A (0.62) | KMT2AMAPTMEN1LMNACD274 | |
| SCHEMBL11727835 | 0.69 | CD274 (0.66) | KMT2AMAPTMEN1LMNACD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021009384-A1 | NOVEL PYRAZOLONE DERIVATIVES AS PD-1/PD-L1 INTERACTION INHIBITORS | CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE LILLE (FR) | 2021-01-21 | — | — | WO | disclosed |