Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22909497 | 0.82 | CES2 (0.34) | — | |
| SCHEMBL22909449 | 0.82 | HDAC3 (0.34) | ALDH1A1GAA | |
| SCHEMBL22909179 | 0.78 | TSHR (0.35) | MEN1KMT2AALDH1A1 | |
| SCHEMBL4142008 | 0.77 | MEN1 (0.42) | MEN1KMT2AALDH1A1MAPTGAA | |
| SCHEMBL22909499 | 0.72 | — | — | |
| SCHEMBL22909437 | 0.69 | — | — | |
| SCHEMBL22909384 | 0.68 | TYMP (0.33) | MAPT | |
| SCHEMBL22909164 | 0.65 | CA12 (0.49) | MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL22909469 | 0.65 | ALDH1A1 (0.37) | ALDH1A1 | |
| SCHEMBL11590135 | 0.64 | MEN1 (0.58) | MEN1KMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021009568-A1 | BENZENESULFONAMIDE DERIVATIVES AND USES THEREOF | 2692372 ONTARIO, INC. (CA) | 2021-01-21 | — | — | WO | disclosed |