Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PLK1 | P53350 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22909456 | 0.82 | MEN1 (0.41) | ALDH1A1GAA | |
| SCHEMBL22909497 | 0.81 | CES2 (0.34) | HDAC6 | |
| SCHEMBL22909600 | 0.73 | IDO1 (0.36) | LMNAGAA | |
| SCHEMBL22909496 | 0.72 | LMNA (0.33) | LMNA | |
| SCHEMBL22909179 | 0.70 | TSHR (0.35) | ALDH1A1 | |
| SCHEMBL6546242 | 0.69 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2PLK1 | |
| SCHEMBL22909499 | 0.68 | — | — | |
| SCHEMBL9035286 | 0.67 | ALDH1A1 (0.55) | HDAC3HDAC6ALDH1A1SMN1; SMN2PLK1 | |
| SCHEMBL22909437 | 0.65 | — | — | |
| SCHEMBL10441340 | 0.63 | HSD17B10 (0.65) | ALDH1A1SMN1; SMN2PLK1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021009568-A1 | BENZENESULFONAMIDE DERIVATIVES AND USES THEREOF | 2692372 ONTARIO, INC. (CA) | 2021-01-21 | — | — | WO | disclosed |