Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 3/20 | 0.37 |
| ▸ | NOS3 | P29474 | 2/20 | 0.37 |
| ▸ | NOS1 | P29475 | 2/20 | 0.37 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28271057 | 1.00 | ALOX15 (0.38) | ALOX15CYP2D6CYP2C9CYP2C19NOS2 | |
| SCHEMBL28269212 | 0.92 | NOD1 (0.40) | ALOX15CYP2D6CYP2C9CYP2C19NOS2 | |
| SCHEMBL28269197 | 0.89 | NOD1 (0.39) | ALOX15CYP2D6CYP2C9CYP2C19NOS2 | |
| SCHEMBL31054715 | 0.85 | CPB2 (0.35) | ALOX15CYP2D6CYP2C9CYP2C19NOS2 | |
| SCHEMBL17282100 | 0.84 | CPB2 (0.39) | ALOX15CYP2D6CYP2C9CYP2C19NOD1 | |
| SCHEMBL1176235 | 0.83 | ALOX15 (0.48) | ALOX15CYP2D6CYP2C9CYP2C19NOD1 | |
| SCHEMBL206673 | 0.82 | CA1 (0.38) | NOS2NOS3NOS1HTT | |
| SCHEMBL1068024 | 0.82 | CA1 (0.38) | NOS2NOS3NOS1HTT | |
| SCHEMBL1688567 | 0.82 | ALOX15 (0.39) | ALOX15CYP2D6CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL17202872 | 0.81 | ALOX15 (0.42) | ALOX15CYP2D6CYP2C9CYP2C19NOD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11339193-B2 | CDP protein secretion inhibitors | KEZAR LIFE SCIENCES (US) | 2022-05-24 | — | — | US | disclosed |
| US-20210017233-A1 | CDP PROTEIN SECRETION INHIBITORS | ENODIA THERAPEUTICS SAS (FR) | 2021-01-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11339193-B2 | CDP protein secretion inhibitors | SEC61G, SEC61A1, SEC61B | ALOX15 3697/4885CYP2D6 3723/4885CYP2C9 4091/4885 |
| US-20210017233-A1 | CDP PROTEIN SECRETION INHIBITORS | SEC61G, SEC61A1, SEC61B | ALOX15 3697/4885CYP2D6 3723/4885CYP2C9 4091/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.