SCHEMBL7542989

SCHEMBL7542989

O=C(O)c1ccc(C(=O)OCc2ccccc2Cl)cc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR4A2 P43354 2/20 0.68
RAB9A P51151 4/20 0.66
MAPT P10636 3/20 0.66
NPC1 O15118 3/20 0.63
L3MBTL1 Q9Y468 2/20 0.62
THRB P10828 1/20 0.58
CASP3 P42574 2/20 0.54
SENP8 Q96LD8 2/20 0.54
SENP7 Q9BQF6 2/20 0.54
SENP6 Q9GZR1 2/20 0.54
MMP1 P03956 1/20 0.54
MMP2 P08253 1/20 0.54
MMP9 P14780 1/20 0.54
MMP12 P39900 1/20 0.54
PPARG P37231 1/20 0.53
HPGD P15428 1/20 0.51
RXRA P19793 1/20 0.51
RXRB P28702 1/20 0.51
TP53 P04637 1/20 0.51
TDP1 Q9NUW8 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5421974 0.92 L3MBTL1 (0.72) NR4A2RAB9AMAPTNPC1L3MBTL1
SCHEMBL831262 0.89 MAPT (0.68) NR4A2RAB9AMAPTNPC1L3MBTL1
SCHEMBL27841681 0.88 PPARG (0.60) NR4A2RAB9AMAPTNPC1PPARG
SCHEMBL14129928 0.84 MAPT (0.63) NR4A2RAB9AMAPTNPC1L3MBTL1
SCHEMBL7536304 0.83 MAPT (0.61) NR4A2RAB9AMAPTNPC1L3MBTL1
SCHEMBL27455851 0.83 RAB9A (0.65) NR4A2RAB9AMAPTNPC1L3MBTL1
SCHEMBL9750057 0.80 RAB9A (0.58) NR4A2RAB9AMAPTNPC1L3MBTL1
SCHEMBL4374949 0.79 L3MBTL1 (0.59) NR4A2RAB9AMAPTNPC1L3MBTL1
SCHEMBL5085480 0.79 PPARG (0.71) RAB9AMAPTL3MBTL1PPARGHPGD
SCHEMBL9750015 0.78 TYR (0.58) RAB9AMAPTNPC1L3MBTL1CASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020094993-A1 Compositions for repelling crawling insects S.C. JOHNSON & SON, INC. 2002-07-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020094993-A1 Compositions for repelling crawling insects ACHE, DDT, GAP43 NR4A2 3917/4885RAB9A 1587/4885MAPT 3240/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.