Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | ACP3 | P15309 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.45 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | GPR139 | Q6DWJ6 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.42 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22917154 | 0.94 | ACP3 (0.47) | MEN1KMT2AACP3ALDH1A1HPGD | |
| SCHEMBL17504249 | 0.91 | BRD4 (0.49) | MEN1KMT2AACP3ALDH1A1HPGD | |
| SCHEMBL22917146 | 0.86 | TRPM8 (0.44) | MEN1KMT2AACP3TRPM8LMNA | |
| SCHEMBL7966754 | 0.85 | MEN1 (0.59) | MEN1KMT2AACP3ALDH1A1HPGD | |
| SCHEMBL22917155 | 0.85 | HDAC4 (0.53) | MEN1KMT2AACP3RAB9A | |
| SCHEMBL12495860 | 0.83 | ALDH1A1 (0.48) | MEN1KMT2AACP3ALDH1A1HPGD | |
| SCHEMBL28419252 | 0.83 | BRD4 (0.55) | MEN1KMT2AHTTTDP1L3MBTL1 | |
| Benzene SCHEMBL27414119 | 0.82 | L3MBTL1 (0.56) | KMT2AALDH1A1HPGDLMNAMAPK1 | |
| SCHEMBL396389 | 0.82 | L3MBTL1 (0.56) | KMT2AALDH1A1HPGDLMNAMAPK1 | |
| SCHEMBL23031986 | 0.81 | MEN1 (0.52) | MEN1KMT2AACP3ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3770148-A1 | RECEPTOR INHIBITOR, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND USE THEREOF | Beijing Tide Pharmaceutical Co., Ltd. (CN) | 2021-01-27 | — | — | EP | disclosed |