Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.37 |
| ▸ | HTR7 | P34969 | 2/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.36 |
| ▸ | EGFR | P00533 | 2/20 | 0.36 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Strictosidine SCHEMBL29456822 | 0.90 | HTR1A (0.56) | HTR1AACHEMEN1KMT2A | |
| Strictosidine SCHEMBL8322946 | 0.90 | HTR1A (0.56) | HTR1AACHEMEN1KMT2A | |
| Strictosidine SCHEMBL29456742 | 0.90 | HTR1A (0.56) | HTR1AACHEMEN1KMT2A | |
| SCHEMBL19353678 | 0.86 | CYP2D6 (0.44) | CYP2D6MEN1KMT2ACASP1HTT | |
| SCHEMBL23675917 | 0.86 | CYP2D6 (0.44) | CYP2D6MEN1KMT2ACASP1HTT | |
| Strictosidinic Acid SCHEMBL4729136 | 0.81 | HTR1A (0.48) | HTR1AACHEGRIN2BPRMT5EGFR | |
| SCHEMBL19353679 | 0.77 | CHRM4 (0.45) | HTR1ACYP2D6MEN1KMT2ACASP1 | |
| SCHEMBL23675939 | 0.73 | GRIN2B (0.44) | CYP2D6MEN1KMT2ACASP1HTT | |
| SCHEMBL2978568 | 0.70 | HTR1A (0.72) | HTR1A | |
| SCHEMBL3205755 | 0.69 | DRD2 (0.48) | MEN1KMT2ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210024944-A1 | METHOD OF PRODUCING ALKALOID | AJINOMOTO CO., INC. (JP) | 2021-01-28 | — | — | US | disclosed |