Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.56 |
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.44 |
| ▸ | STAT3 | P40763 | 12/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Strictosidine SCHEMBL29456822 | 1.00 | HTR1A (0.56) | HTR1AACHEPOLBCTDSP1STAT3 | |
| Strictosidine SCHEMBL29456742 | 1.00 | HTR1A (0.56) | HTR1AACHEPOLBCTDSP1STAT3 | |
| Strictosidinic Acid SCHEMBL4729136 | 0.92 | HTR1A (0.48) | HTR1AACHEPOLBCTDSP1STAT3 | |
| SCHEMBL22919319 | 0.90 | HTR1A (0.47) | HTR1AACHEMEN1KMT2A | |
| SCHEMBL19353678 | 0.84 | CYP2D6 (0.44) | MEN1KMT2A | |
| SCHEMBL4097773 | 0.80 | DRD2 (0.48) | POLBCTDSP1STAT3MEN1MAPT | |
| SCHEMBL3205755 | 0.80 | DRD2 (0.48) | POLBCTDSP1STAT3MEN1MAPT | |
| SCHEMBL2978568 | 0.79 | HTR1A (0.72) | HTR1ASTAT3MAPT | |
| Secologanin SCHEMBL22658018 | 0.77 | HTR1A (0.68) | HTR1AACHESTAT3MEN1MAPT | |
| SCHEMBL30004407 | 0.77 | HTR1A (0.46) | HTR1AACHEPOLBCTDSP1STAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210024944-A1 | METHOD OF PRODUCING ALKALOID | AJINOMOTO CO., INC. (JP) | 2021-01-28 | — | — | US | disclosed |
| WO-2004113336-A1 | CARBOLINE AND BETACARBOLINE DERIVATIVES FOR USE AS HDAC ENZYME INHIBITORS | CHROMA THERAPEUTICS LIMITED (GB) | 2004-12-29 | — | — | WO | disclosed |