Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 1/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 5/20 | 0.44 |
| ▸ | HTR7 | P34969 | 5/20 | 0.44 |
| ▸ | DRD2 | P14416 | 2/20 | 0.44 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.43 |
| ▸ | EGFR | P00533 | 2/20 | 0.43 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | HTR2C | P28335 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19353679 | 0.87 | CHRM4 (0.45) | GRIN2BCHRM4HTR7DRD2PRMT5 | |
| SCHEMBL19353678 | 0.80 | CYP2D6 (0.44) | GRIN2BCHRM4HTR7DRD2PRMT5 | |
| SCHEMBL23675917 | 0.80 | CYP2D6 (0.44) | GRIN2BCHRM4HTR7DRD2PRMT5 | |
| SCHEMBL22919319 | 0.73 | HTR1A (0.47) | GRIN2BCHRM4HTR7DRD2PRMT5 | |
| SCHEMBL8322968 | 0.71 | GRIN2B (0.70) | GRIN2BCHRM4HTR7DRD2MAPKAPK2 | |
| SCHEMBL29756361 | 0.71 | GRIN2B (0.70) | GRIN2BCHRM4HTR7DRD2MAPKAPK2 | |
| SCHEMBL21883968 | 0.71 | GRIN2B (0.70) | GRIN2BCHRM4HTR7DRD2MAPKAPK2 | |
| Strictosidine SCHEMBL29456742 | 0.71 | HTR1A (0.56) | MEN1KMT2A | |
| Strictosidine SCHEMBL8322946 | 0.71 | HTR1A (0.56) | MEN1KMT2A | |
| Strictosidine SCHEMBL29456822 | 0.71 | HTR1A (0.56) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11072613-B2 | Compositions and methods for making terpenoid indole alkaloids | WILLOW BIOSCIENCES, INC. (CA) | 2021-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11072613-B2 | Compositions and methods for making terpenoid indole alkaloids | INMT, TIPARP, PNMT | GRIN2B 4103/4885CHRM4 2703/4885HTR7 184/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.