Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 4/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 3/20 | 0.35 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22921050 | 0.84 | ALDH1A1 (0.38) | ESR1ESR2IDO1TAAR1PDE2A | |
| SCHEMBL2600028 | 0.82 | IDO1 (0.54) | IDO1TAAR1DAOAPPPDE2A | |
| SCHEMBL23790349 | 0.82 | ESR1 (0.43) | ESR1IDO1 | |
| SCHEMBL18711204 | 0.75 | ESR1 (0.36) | ESR1TAAR1PDE2AALDH1A1 | |
| SCHEMBL16116513 | 0.74 | CYP4F2 (0.40) | ESR1 | |
| SCHEMBL18701033 | 0.73 | CYP1A2 (0.43) | IDO1DAOALDH1A1 | |
| SCHEMBL1691810 | 0.72 | ESR1 (0.54) | ESR1ESR2IDO1TAAR1MAOB | |
| SCHEMBL13021064 | 0.72 | IDO1 (0.54) | IDO1TAAR1DAOPDE2A | |
| SCHEMBL24418507 | 0.71 | GABRA1 (0.43) | ESR1 | |
| SCHEMBL16116515 | 0.70 | ESR1 (0.44) | ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12043674-B2 | Synthetic cyclic peptides and methods of preparation and use thereof | AUBURN UNIVERSITY (US) | 2024-07-23 | — | — | US | disclosed |
| US-11339184-B2 | Antibacterial compounds, compositions thereof, and methods using same | THE ROCKEFELLER UNIVERSITY (US) | 2022-05-24 | — | — | US | disclosed |
| US-20220119445-A1 | SYNTHETIC CYCLIC PEPTIDES AND METHODS OF PREPARATION AND USE THEREOF | NATIONAL SCIENCE FOUNDATION | 2022-04-21 | — | — | US | disclosed |
| US-20210024562-A1 | ANTIBACTERIAL COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS USING SAME | THE ROCKEFELLER UNIVERSITY | 2021-01-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11339184-B2 | Antibacterial compounds, compositions thereof, and methods using same | CLPP, MPO, SPOUT1 | ESR1 4377/4885ESR2 4162/4885IDO1 2564/4885 |
| US-12043674-B2 | Synthetic cyclic peptides and methods of preparation and use thereof | VIP, PTMS, IAPP | ESR1 4263/4885ESR2 3840/4885IDO1 2643/4885 |
| US-20220119445-A1 | SYNTHETIC CYCLIC PEPTIDES AND METHODS OF PREPARATION AND USE THEREOF | VIP, PTMS, IAPP | ESR1 4263/4885ESR2 3840/4885IDO1 2643/4885 |
| US-20210024562-A1 | ANTIBACTERIAL COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS USING SAME | CLPP, MPO, SPOUT1 | ESR1 4377/4885ESR2 4162/4885IDO1 2564/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.