SCHEMBL22922065

SCHEMBL22922065

CC(C)(CO)CCCCc1cccc(CCCCC(C)(C)CO)c1

nearest known ligand 0.43

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LPL P06858 2/20 0.41
LIPG Q9Y5X9 2/20 0.41
CYP4F2 P78329 1/20 0.41
CYP4A11 Q02928 1/20 0.41
PPARG P37231 2/20 0.39
PPARA Q07869 2/20 0.39
NOS1 P29475 1/20 0.39
IGF1R P08069 1/20 0.38
ALOX15 P16050 1/20 0.38
HMGCR P04035 1/20 0.38
TNNC1 P63316 5/20 0.37
SGPL1 O95470 1/20 0.37
S1PR4 O95977 1/20 0.37
S1PR1 P21453 1/20 0.37
GPR183 P32249 1/20 0.37
CERS2 Q96G23 1/20 0.37
S1PR3 Q99500 1/20 0.37
S1PR5 Q9H228 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31671190 0.87 TAAR1 (0.45) LPLLIPGPPARGPPARA
SCHEMBL2284133 0.87 L3MBTL1 (0.46) IGF1RALOX15
SCHEMBL27736912 0.80 LPL (0.42) LPLLIPGCYP4F2CYP4A11PPARG
SCHEMBL25996677 0.80 FFAR1 (0.56) CYP4F2CYP4A11PPARGPPARA
SCHEMBL10235739 0.79 LPL (0.46) LPLLIPGPPARGPPARAALOX15
SCHEMBL6714707 0.78 L3MBTL1 (0.38)
SCHEMBL6259778 0.76 NAAA (0.37)
SCHEMBL610875 0.76 MEN1 (0.40) LPLLIPGPPARGPPARANOS1
SCHEMBL26019022 0.76 CYP4F2 (0.47) CYP4F2CYP4A11PPARGPPARA
SCHEMBL22921342 0.75 LTB4R (0.57) PPARGPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4003314-B1 FUNCTIONALIZED LONG-CHAIN HYDROCARBON MONO- AND DI-CARBOXYLIC ACIDS USEFUL FOR THE PREVENTION OR TREATMENT OF DISEASE ESPERVITA THERAPEUTICS INC (US) 2024-07-10 EP disclosed
CN-118119386-A Functionalized carboxylic acids and their use for treating diseases 埃斯佩尔维塔治疗股份有限公司 2024-05-31 CN disclosed
EP-4281058-A2 FUNCTIONALIZED LONG-CHAIN CARBOXYLIC ACIDS, AND THEIR USE FOR TREATMENT OF DISEASE Espervita Therapeutics, Inc. (US) 2023-11-29 EP disclosed
US-11737995-B2 Functionalized long-chain hydrocarbon mono- and di-carboxylic acids and derivatives thereof, and their use for the prevention or treatment of disease ESPERVITA THERAPEUTICS, INC. (US) 2023-08-29 US disclosed
US-11737995-B2 Functionalized long-chain hydrocarbon mono- and di-carboxylic acids and derivatives thereof, and their use for the prevention or treatment of disease ESPERVITA THERAPEUTICS, INC. (US) 2023-08-29 US disclosed
US-11730712-B2 Functionalized long-chain hydrocarbon mono- and di-carboxylic acids and derivatives thereof, and their use for the prevention or treatment of disease ESPERVITA THERAPEUTICS, INC. (US) 2023-08-22 US disclosed
US-11730712-B2 Functionalized long-chain hydrocarbon mono- and di-carboxylic acids and derivatives thereof, and their use for the prevention or treatment of disease ESPERVITA THERAPEUTICS, INC. (US) 2023-08-22 US disclosed
US-20230007838-A1 FUNCTIONALIZED LONG-CHAIN HYDROCARBON MONO- AND DI-CARBOXYLIC ACIDS AND THEIR USE FOR THE PREVENTION OR TREATMENT OF DISEASE ESPERVITA THERAPEUTICS, INC. 2023-01-12 US disclosed
US-20220402851-A1 FUNCTIONALIZED LONG-CHAIN HYDROCARBON MONO- AND DI-CARBOXYLIC ACIDS AND THEIR USE FOR THE PREVENTION OR TREATMENT OF DISEASE ESPERVITA THERAPEUTICS, INC. 2022-12-22 US disclosed
WO-2022159808-A2 FUNCTIONALIZED LONG-CHAIN HYDROCARBON MONO- AND DI-CARBOXYLIC ACIDS AND DERIVATIVES THEREOF, AND THEIR USE FOR THE PREVENTION OR TREATMENT OF DISEASE ESPERVITA THERAPEUTICS, INC. (US) 2022-07-28 WO disclosed
WO-2022159811-A1 FUNCTIONALIZED LONG-CHAIN HYDROCARBON MONO- AND DI-CARBOXYLIC ACIDS AND DERIVATIVES THEREOF, AND THEIR USE FOR THE PREVENTION OR TREATMENT OF DISEASE ESPERVITA THERAPEUTICS, INC. (US) 2022-07-28 WO disclosed
EP-4003314-A1 FUNCTIONALIZED LONG-CHAIN HYDROCARBON MONO- AND DI-CARBOXYLIC ACIDS USEFUL FOR THE PREVENTION OR TREATMENT OF DISEASE Espervita Therapeutics, Inc. (US) 2022-06-01 EP disclosed
CN-114126593-A Functionalized long chain hydrocarbon mono-and dicarboxylic acids useful for preventing or treating disease 埃斯佩尔维塔治疗股份有限公司 2022-03-01 CN disclosed
US-11084773-B1 Functionalized long-chain hydrocarbon mono- and di-carboxylic acids and their use for the prevention or treatment of disease ESPERVITA THERAPEUTICS, INC. (US) 2021-08-10 US disclosed
US-20210221765-A1 FUNCTIONALIZED LONG-CHAIN HYDROCARBON MONO- AND DI-CARBOXYLIC ACIDS AND THEIR USE FOR THE PREVENTION OR TREATMENT OF DISEASE ESPERVITA THERAPEUTICS, INC. 2021-07-22 US disclosed
US-20210024447-A1 FUNCTIONALIZED LONG-CHAIN HYDROCARBON MONO- AND DI-CARBOXYLIC ACIDS AND THEIR USE FOR THE PREVENTION OR TREATMENT OF DISEASE ESPERVITA THERAPEUTICS, INC. 2021-01-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230007838-A1 FUNCTIONALIZED LONG-CHAIN HYDROCARBON MONO- AND DI-CARBOXYLIC ACIDS AND THEIR USE FOR THE PREVENTION OR TREATMENT OF DISEASE CPT1A, PPARG, PC LPL 138/4885LIPG 153/4885CYP4F2 708/4885
US-20210221765-A1 FUNCTIONALIZED LONG-CHAIN HYDROCARBON MONO- AND DI-CARBOXYLIC ACIDS AND THEIR USE FOR THE PREVENTION OR TREATMENT OF DISEASE CPT1A, PPARG, PC LPL 138/4885LIPG 159/4885CYP4F2 708/4885
US-11737995-B2 Functionalized long-chain hydrocarbon mono- and di-carboxylic acids and derivatives thereof, and their use for the prevention or treatment of disease AHR, PKD1, CFTR LPL 2880/4885LIPG 2541/4885CYP4F2 687/4885
US-11084773-B1 Functionalized long-chain hydrocarbon mono- and di-carboxylic acids and their use for the prevention or treatment of disease CPT1A, PPARG, PC LPL 138/4885LIPG 159/4885CYP4F2 708/4885
US-11730712-B2 Functionalized long-chain hydrocarbon mono- and di-carboxylic acids and derivatives thereof, and their use for the prevention or treatment of disease CPT1A, PPARG, PC LPL 157/4885LIPG 163/4885CYP4F2 674/4885
US-20210024447-A1 FUNCTIONALIZED LONG-CHAIN HYDROCARBON MONO- AND DI-CARBOXYLIC ACIDS AND THEIR USE FOR THE PREVENTION OR TREATMENT OF DISEASE CPT1A, PPARG, PC LPL 138/4885LIPG 159/4885CYP4F2 708/4885
US-20220402851-A1 FUNCTIONALIZED LONG-CHAIN HYDROCARBON MONO- AND DI-CARBOXYLIC ACIDS AND THEIR USE FOR THE PREVENTION OR TREATMENT OF DISEASE CPT1A, PPARG, PC LPL 138/4885LIPG 153/4885CYP4F2 708/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.