Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 4/20 | 0.56 |
| ▸ | CTSL | P07711 | 2/20 | 0.56 |
| ▸ | CTSB | P07858 | 2/20 | 0.56 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | ALPI | P09923 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | XIAP | P98170 | 1/20 | 0.47 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.47 |
| ▸ | MMP12 | P39900 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3008826 | 1.00 | CTSK (0.56) | CTSKCTSLCTSBSLC18A3ALDH1A1 | |
| SCHEMBL1837096 | 0.87 | CTSK (0.57) | CTSKCTSLCTSBALPIPKM | |
| SCHEMBL2289952 | 0.86 | CTSK (0.56) | CTSKCTSLCTSBALDH1A1ALPI | |
| SCHEMBL12378816 | 0.86 | CTSK (0.56) | CTSKCTSLCTSBALDH1A1ALPI | |
| SCHEMBL8921434 | 0.84 | ALDH1A1 (0.46) | CTSKCTSLCTSBALDH1A1ALPI | |
| SCHEMBL21976912 | 0.84 | CTSK (0.55) | CTSKCTSLCTSBALPIPKM | |
| SCHEMBL28665539 | 0.84 | CTSL (0.42) | CTSKCTSLCTSBSLC18A3ALDH1A1 | |
| SCHEMBL9280171 | 0.84 | CTSK (0.55) | CTSKCTSLCTSBALPIPKM | |
| SCHEMBL28199415 | 0.83 | CTSK (0.51) | CTSKCTSLCTSBALDH1A1ALPI | |
| SCHEMBL8811765 | 0.83 | MMP12 (0.48) | CTSKCTSLCTSBALDH1A1ALPI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304223-B2 | Isoforms of pig liver esterase | ENZYMICALS AG (DE) | 2012-11-06 | — | — | US | disclosed |
| US-20110207186-A1 | Isoforms of Pig Liver Esterase | ENZYMICALS AG (DE) | 2011-08-25 | — | — | US | disclosed |
| US-7229817-B2 | Recombinant porcine liver esterases, their use and a method for the production thereof | DEGUSSA AG (DE) | 2007-06-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110207186-A1 | Isoforms of Pig Liver Esterase | CES1, PIGO, PIGS | CTSK 1846/4885CTSL 1341/4885CTSB 1339/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.