Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.55 |
| ▸ | MEN1 | O00255 | 6/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | IDO1 | P14902 | 2/20 | 0.55 |
| ▸ | TDO2 | P48775 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | CASP6 | P55212 | 1/20 | 0.55 |
| ▸ | MPI | P34949 | 1/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 5/20 | 0.46 |
| ▸ | TP53 | P04637 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 4/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22446564 | 0.87 | COMT (0.50) | KDM4EL3MBTL1MEN1KMT2ATDP1 | |
| SCHEMBL16207365 | 0.81 | KDM4E (0.62) | KDM4EL3MBTL1MEN1KMT2ATDP1 | |
| SCHEMBL737088 | 0.79 | KDM4E (0.50) | KDM4EL3MBTL1MEN1KMT2ATDP1 | |
| SCHEMBL22446563 | 0.77 | L3MBTL1 (0.57) | KDM4EL3MBTL1MEN1KMT2ATDP1 | |
| SCHEMBL113528 | 0.77 | KDM4E (0.72) | KDM4EL3MBTL1MEN1KMT2ATDP1 | |
| SCHEMBL113119 | 0.77 | KDM4E (0.72) | KDM4EL3MBTL1MEN1KMT2ATDP1 | |
| SCHEMBL115570 | 0.77 | KDM4E (0.72) | KDM4EL3MBTL1MEN1KMT2ATDP1 | |
| SCHEMBL4457883 | 0.77 | HSP90AA1 (0.72) | KDM4EL3MBTL1MEN1KMT2ATDP1 | |
| SCHEMBL14302133 | 0.76 | KDM4E (0.66) | KDM4EL3MBTL1MEN1KMT2ATDP1 | |
| SCHEMBL7688612 | 0.73 | KDM4E (0.60) | KDM4EL3MBTL1MEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210024468-A1 | 8-HYDROXYQUINOLINE DERIVATIVES AS DIAGNOSTIC AND THERAPEUTIC AGENTS | THE GENERAL HOSPITAL CORPORATION | 2021-01-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210024468-A1 | 8-HYDROXYQUINOLINE DERIVATIVES AS DIAGNOSTIC AND THERAPEUTIC AGENTS | KLK3, COQ8A, PARK7 | KDM4E 2935/4885L3MBTL1 3167/4885MEN1 72/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.