Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 7/20 | 0.42 |
| ▸ | FLT1 | P17948 | 2/20 | 0.39 |
| ▸ | FLT4 | P35916 | 2/20 | 0.39 |
| ▸ | KDR | P35968 | 2/20 | 0.39 |
| ▸ | KIT | P10721 | 1/20 | 0.38 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.38 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | VCP | P55072 | 1/20 | 0.35 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31755987 | 0.89 | TRPV1 (0.39) | TRPV1FLT1FLT4KDRKIT | |
| SCHEMBL22925705 | 0.86 | FLT1 (0.46) | TRPV1FLT1FLT4KDRKIT | |
| SCHEMBL28733676 | 0.86 | TRPV1 (0.41) | TRPV1FLT1FLT4KDRKIT | |
| SCHEMBL22925873 | 0.83 | IMPDH2 (0.45) | TRPV1FLT1FLT4KDRKIT | |
| SCHEMBL22925800 | 0.79 | TRPV1 (0.51) | TRPV1FLT1KDRKITVCP | |
| SCHEMBL29621081 | 0.77 | GSK3B (0.41) | TRPV1FLT1FLT4KDRKIT | |
| SCHEMBL22926054 | 0.77 | GSK3B (0.41) | TRPV1FLT1FLT4KDRKIT | |
| SCHEMBL22925774 | 0.76 | TRPV1 (0.48) | TRPV1FLT1FLT4KDRIMPDH2 | |
| SCHEMBL22926050 | 0.76 | NPSR1 (0.39) | TRPV1FLT1FLT4KDRKIT | |
| SCHEMBL29620970 | 0.76 | NPSR1 (0.39) | TRPV1FLT1FLT4KDRKIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4003986-A1 | INHIBITOR COMPOUNDS | Cincera Therapeutics Pty Ltd (AU) | 2022-06-01 | — | — | EP | disclosed |