SCHEMBL2292585

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2292860	0.83	KDM4E (0.57)	NPC1RAB9AALDH1A1SMN1; SMN2HPGD
	SCHEMBL3407191	0.82	NPC1 (0.46)	HCAR2NPC1RAB9AALDH1A1MAPT
	SCHEMBL2291080	0.81	KDM4E (0.56)	ALDH1A1HTT
	SCHEMBL12378355	0.80	ADRB1 (0.56)	ALDH1A1MAPT
	SCHEMBL2825832	0.78	TDP1 (0.48)	—
	SCHEMBL12378430	0.77	ADRB1 (0.59)	ALDH1A1MAPTHTT
	SCHEMBL2825229	0.77	CACNA2D1 (0.50)	—
	SCHEMBL12378457	0.76	ADRB1 (0.54)	MAPTHTT
	SCHEMBL12378470	0.76	ME2 (0.55)	NPC1MAPTGAA
	SCHEMBL12378468	0.76	ME2 (0.55)	NPC1MAPTGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.