SCHEMBL22927008

SCHEMBL22927008

c1ccc(-c2ccc(-n3c4ccc5ccccc5c4c4c5ccccc5ccc43)c3ccccc23)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 1/20 0.38
TDP1 Q9NUW8 3/20 0.38
MAPT P10636 4/20 0.38
KDM4E B2RXH2 3/20 0.38
ALDH1A1 P00352 3/20 0.38
HPGD P15428 3/20 0.38
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
TNF P01375 1/20 0.36
CYP1A1 P04798 3/20 0.35
CYP1A2 P05177 3/20 0.35
ABCG2 Q9UNQ0 3/20 0.35
CYP1B1 Q16678 2/20 0.35
FYN P06241 1/20 0.35
MAPK3 P27361 1/20 0.35
AHR P35869 1/20 0.35
PAX8 Q06710 1/20 0.35
HSD17B10 Q99714 3/20 0.34
TSHR P16473 2/20 0.34
CYP2A6 P11509 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22141332 0.89 KDM4E (0.36) HTR6TDP1MAPTKDM4EALDH1A1
SCHEMBL17179088 0.87 KDM4E (0.43) TDP1MAPTKDM4EALDH1A1HPGD
SCHEMBL17178551 0.87 MAPT (0.37) TDP1MAPTKDM4EALDH1A1HPGD
SCHEMBL21117288 0.87 HTR6 (0.40) HTR6MAPTKDM4EALDH1A1MEN1
SCHEMBL21524308 0.86 MAPT (0.35) HTR6TDP1MAPTKDM4EALDH1A1
SCHEMBL24152707 0.86 MAPT (0.39) TDP1MAPTKDM4EALDH1A1HPGD
SCHEMBL24153055 0.85 MAPT (0.34) HTR6TDP1MAPTKDM4EALDH1A1
SCHEMBL17179112 0.84 ALDH1A1 (0.43) TDP1MAPTKDM4EALDH1A1HPGD
SCHEMBL18019464 0.83 MAPT (0.42) TDP1MAPTKDM4EALDH1A1HPGD
SCHEMBL18876969 0.83 L3MBTL1 (0.41) TDP1MAPTKDM4EALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230329107-A1 PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2023-10-12 US disclosed
US-20230329107-A1 PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2023-10-12 US disclosed
US-11706984-B2 Plurality of host materials and organic electroluminescent device comprising the same ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. 2023-07-18 US disclosed
US-11706984-B2 Plurality of host materials and organic electroluminescent device comprising the same ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. 2023-07-18 US disclosed
US-20220384744-A1 A PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2022-12-01 US disclosed
US-20210193933-A1 PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM & HAAS ELECT MATERIALS KOREA LTD (KR) 2021-06-24 US disclosed
US-20210126203-A1 PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2021-04-29 US disclosed
US-20210028373-A1 A PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2021-01-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210028373-A1 A PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME TERT, TELO2, LIMS1 HTR6 3622/4885TDP1 355/4885MAPT 1849/4885
US-20220384744-A1 A PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME TELO2, PIEZO1, LIMS1 HTR6 3608/4885TDP1 414/4885MAPT 2509/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.