SCHEMBL2292995

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL135004	0.86	KLF10 (0.36)	CYP2D6CYP2C19CYP1A2CYP2C9HIF1A
	SCHEMBL2288353	0.84	PDE2A (0.34)	CYP2D6CYP2C19CYP1A2CYP2C9HIF1A
	SCHEMBL30558280	0.83	CYP1A2 (0.44)	CYP2D6CYP2C19CYP1A2CYP2C9HIF1A
	SCHEMBL1320175	0.83	CYP1A2 (0.44)	CYP2D6CYP2C19CYP1A2CYP2C9HIF1A
	SCHEMBL11542336	0.83	CYP2D6 (0.42)	CYP2D6CYP2C19CYP1A2CYP2C9HIF1A
	SCHEMBL8762233	0.83	CYP2C19 (0.47)	CYP2D6CYP2C19CYP1A2CYP2C9HIF1A
	SCHEMBL31012297	0.83	CYP2C19 (0.47)	CYP2D6CYP2C19CYP1A2CYP2C9HIF1A
	SCHEMBL27012358	0.80	CYP2D6 (0.40)	CYP2D6CYP2C19CYP1A2CYP2C9HIF1A
	SCHEMBL29382636	0.79	IDO1 (0.41)	CYP2D6MAPTTSHRNPSR1
	SCHEMBL475304	0.79	IDO1 (0.41)	CYP2D6MAPTTSHRNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.