Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | GPR6 | P46095 | 2/20 | 0.43 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22933040 | 0.85 | GPR119 (0.53) | LMNAGPR119SMN1; SMN2MAPTKMT2A | |
| SCHEMBL22932935 | 0.84 | GPR119 (0.48) | KIF18AGPR119TRPA1 | |
| SCHEMBL22933034 | 0.82 | PKM (0.50) | LMNASMN1; SMN2MAPTMAPK1HTT | |
| SCHEMBL29826099 | 0.78 | GLP1R (0.53) | GPR119 | |
| SCHEMBL20266356 | 0.78 | GLP1R (0.53) | GPR119 | |
| SCHEMBL22936006 | 0.77 | KIF18A (0.57) | KIF18AGPR119SMN1; SMN2HTTKMT2A | |
| SCHEMBL355131 | 0.76 | GPR119 (0.68) | GPR119 | |
| SCHEMBL29378266 | 0.76 | GPR119 (0.68) | GPR119 | |
| SCHEMBL24574904 | 0.75 | GLP1R (0.51) | GPR119 | |
| SCHEMBL31025621 | 0.75 | GLP1R (0.51) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021018023-A1 | SMALL MOLECULE GLP-1 RECEPTOR MODULATOR | 济南泰达领创医药技术有限公司 | 2021-02-04 | — | — | WO | disclosed |