SCHEMBL2293474

SCHEMBL2293474

CCCCC(CCC)c1cc(O)c(-c2c(O)cc(C(CCC)CCCC)cc2C(C)(C)C)c(C(C)(C)C)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 2/20 0.40
CYP2D6 P10635 2/20 0.40
TP53 P04637 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40
NPSR1 Q6W5P4 2/20 0.39
GAA P10253 1/20 0.39
XBP1 P17861 1/20 0.39
ATM Q13315 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
CYP1A2 P05177 2/20 0.33
KDM4E B2RXH2 1/20 0.33
ALDH1A1 P00352 1/20 0.33
MAPT P10636 1/20 0.33
ATP2A2 P16615 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
ATP2A3 Q93084 1/20 0.33
CNR1 P21554 1/20 0.31
CNR2 P34972 1/20 0.31
ESR1 P03372 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2295800 0.94 ALOX15 (0.44) ALOX15CYP2D6TP53CYP2C9CYP2C19
SCHEMBL2292908 0.91 NPSR1 (0.41) ALOX15CYP2D6TP53CYP2C9CYP2C19
SCHEMBL2291030 0.88 ALOX15 (0.42) ALOX15CYP2D6TP53CYP2C9CYP2C19
SCHEMBL2293692 0.83 GAA (0.39) ALOX15CYP2D6TP53CYP2C9CYP2C19
SCHEMBL15065448 0.82 CYP2C9 (0.37) ALOX15CYP2D6TP53CYP2C9CYP2C19
SCHEMBL27607951 0.80 CA2 (0.40) ALOX15CYP2D6TP53CYP2C9CYP2C19
SCHEMBL2289500 0.79 KDR (0.37) ALOX15CYP2D6TP53CYP2C9CYP2C19
SCHEMBL2290751 0.78 KDR (0.39) ALOX15CYP2D6TP53CYP2C9CYP2C19
SCHEMBL15065029 0.74 CYP2C9 (0.41) ALOX15CYP2D6TP53CYP2C9CYP2C19
SCHEMBL31545536 0.73 ADRB2 (0.50) ESR1ESR2ADRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2346887-B1 SLURRY PROCESS FOR SYNTHESIS OF BISPHOSPHITES DOW TECHNOLOGY INVESTMENTS LLC (US) 2013-12-25 EP disclosed
US-8546600-B2 Slurry process for synthesis of bisphosphites and situ use thereof for producing bisphosphite DOW TECHNOLOGY INVESTMENTS LLC 2013-10-01 US disclosed
US-20110196166-A1 SLURRY PROCESS FOR SYNTHESIS OF BISPHOSPHITES AND SITU USE THEREOF FOR PRODUCING BISPHOSPHITE DOW TECHNOLOGY INVESTMENTS LLC 2011-08-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110196166-A1 SLURRY PROCESS FOR SYNTHESIS OF BISPHOSPHITES AND SITU USE THEREOF FOR PRODUCING BISPHOSPHITE SOST, PLCB3, PPIP5K2 ALOX15 2202/4885CYP2D6 2753/4885TP53 4772/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.