Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 4/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.52 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.52 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 4/20 | 0.42 |
| ▸ | PPARD | Q03181 | 4/20 | 0.42 |
| ▸ | PPARA | Q07869 | 4/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adipic Acid SCHEMBL16670398 | 1.00 | LMNA (0.55) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Adipic Acid SCHEMBL336949 | 1.00 | LMNA (0.55) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Adipic Acid SCHEMBL5874393 | 1.00 | LMNA (0.55) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Adipic Acid SCHEMBL18091137 | 0.98 | LMNA (0.52) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Sebacic Acid SCHEMBL5875002 | 0.98 | TSHR (0.57) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Adipic Acid SCHEMBL2293630 | 0.98 | LMNA (0.52) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Sebacic Acid SCHEMBL11610099 | 0.98 | TSHR (0.57) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Sebacic Acid SCHEMBL5874996 | 0.98 | TSHR (0.57) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Azepane SCHEMBL18063297 | 0.95 | TSHR (0.55) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Azelaic Acid SCHEMBL2699067 | 0.95 | TSHR (0.55) | LMNATSHRNFKB1PMP22SLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1041738-C | Compositions of vulcanize rubbers | MITSUI PETROCHEMICAL IND (JP) | 1999-01-20 | — | — | CN | claimed |
| EP-0292263-B1 | VULCANIZABLE RUBBER COMPOSITION | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1993-07-14 | — | — | EP | claimed |
| CN-1069747-A | Compositions of vulcanize rubbers | MITSUI PETROCHEMICAL INDUSTXIE (JP) | 1993-03-10 | — | — | CN | claimed |
| US-5004787-A | With aliphatic or aromatic carboxylic acid amine salts or phenolic amine salts as promoters in chlorinated rubbers | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1991-04-02 | — | — | US | claimed |
| CN-1037719-A | VULCANIZABLE RUBBER COMPOSITION | MITSUI PETROCHEMICAL IND (JP) | 1989-12-06 | — | — | CN | claimed |
| EP-0292263-A2 | Vulcanizable rubber composition | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1988-11-23 | — | — | EP | claimed |
| US-7128976-B2 | Composition for film formation, method of film formation, and silica-based film | JSR CORPORATION (JP) | 2006-10-31 | — | — | US | disclosed |
| US-20030091838-A1 | Composition for film formation, method of film formation, and silica-based film | JSR CORPORATION (JP) | 2003-05-15 | — | — | US | disclosed |
| CN-1041738-C | Compositions of vulcanize rubbers | MITSUI PETROCHEMICAL IND (JP) | 1999-01-20 | — | — | CN | disclosed |
| CN-1027378-C | Vulcanizable rubber composition | MITSUI PETROCHEMICAL IND (JP) | 1995-01-11 | — | — | CN | disclosed |
| US-5310818-A | Vulcanizable chlorine-containing rubber compositions containing triazinethiol amine salt vulcanizing agents | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1994-05-10 | — | — | US | disclosed |
| EP-0292263-B1 | VULCANIZABLE RUBBER COMPOSITION | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1993-07-14 | — | — | EP | disclosed |
| CN-1069747-A | Compositions of vulcanize rubbers | MITSUI PETROCHEMICAL INDUSTXIE (JP) | 1993-03-10 | — | — | CN | disclosed |
| US-5004787-A | With aliphatic or aromatic carboxylic acid amine salts or phenolic amine salts as promoters in chlorinated rubbers | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1991-04-02 | — | — | US | disclosed |
| CN-1037719-A | VULCANIZABLE RUBBER COMPOSITION | MITSUI PETROCHEMICAL IND (JP) | 1989-12-06 | — | — | CN | disclosed |
| EP-0292263-A2 | Vulcanizable rubber composition | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1988-11-23 | — | — | EP | disclosed |