Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 4/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.52 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.52 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 4/20 | 0.42 |
| ▸ | PPARD | Q03181 | 4/20 | 0.42 |
| ▸ | PPARA | Q07869 | 4/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adipic Acid SCHEMBL5874403 | 1.00 | LMNA (0.55) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Adipic Acid SCHEMBL16670398 | 1.00 | LMNA (0.55) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Adipic Acid SCHEMBL5874393 | 1.00 | LMNA (0.55) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Adipic Acid SCHEMBL18091137 | 0.98 | LMNA (0.52) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Sebacic Acid SCHEMBL5875002 | 0.98 | TSHR (0.57) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Adipic Acid SCHEMBL2293630 | 0.98 | LMNA (0.52) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Sebacic Acid SCHEMBL11610099 | 0.98 | TSHR (0.57) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Sebacic Acid SCHEMBL5874996 | 0.98 | TSHR (0.57) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Azepane SCHEMBL18063297 | 0.95 | TSHR (0.55) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Azelaic Acid SCHEMBL2699067 | 0.95 | TSHR (0.55) | LMNATSHRNFKB1PMP22SLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4101534-A | ALIPHATIC POLYAMIDES | TOYO SEIKAN KAISHA LIMITED (JP) | 1978-07-18 | — | — | US | claimed |
| JP-5025269-A | — | — | None | — | — | JP | disclosed |
| JP-60217238-A | — | — | None | — | — | JP | disclosed |
| US-10065400-B2 | Fuel hose | SUMITOMO RIKO COMPANY LIMITED (JP) | 2018-09-04 | — | — | US | disclosed |
| EP-2824235-B1 | CARBON FIBER BUNDLE AND PROCESS FOR PRODUCING SAME | TEIJIN LTD (JP) | 2018-08-01 | — | — | EP | disclosed |
| EP-2570459-B1 | POLYAMIDE RESIN COMPOSITION | MITSUBISHI GAS CHEMICAL CO (JP) | 2018-02-21 | — | — | EP | disclosed |
| WO-2017181173-A1 | SOLID STATE CONVERSION OF BIO-BASED ORGANIC SALTS TO GENERATE POLYMER COATINGS | THE UNIVERSITY OF AKRON (US) | 2017-10-19 | — | — | WO | disclosed |
| EP-2003158-B1 | DENDRITIC POLYESTER, METHOD FOR PRODUCING THE SAME, AND THERMOPLASTIC RESIN COMPOSITION | TORAY INDUSTRIES (JP) | 2017-07-05 | — | — | EP | disclosed |
| US-20170145627-A1 | Reinforcing Fiber Bundle and Method for Producing Same | TEIJIN LIMITED (JP) | 2017-05-25 | — | — | US | disclosed |
| US-9506169-B2 | Carbon fiber bundle and manufacturing method of the same | TEIJIN LIMITED (JP) | 2016-11-29 | — | — | US | disclosed |
| WO-2002031042-A2 | METHOD FOR ADDING INORGANIC ADDITIVES TO FINISHED POLYMER MELTS | SACHTLEBEN CHEMIE GMBH (DE) | 2002-04-18 | — | — | WO | disclosed |
| WO-2002030994-A1 | METHOD FOR ADDING INORGANIC ADDITIVES TO POLYMER RAW MATERIAL BEFORE POLYMER FORMATION | SACHTLEBEN CHEMIE GMBH (DE) | 2002-04-18 | — | — | WO | disclosed |
| WO-2002008171-A2 | METHOD FOR SEPARATING AMMONIAC | BASF AKTIENGESELLSCHAFT (DE) | 2002-01-31 | — | — | WO | disclosed |
| EP-0852249-A1 | POLYPHENYLENE SULFIDE RESIN COMPOSITION | TORAY INDUSTRIES, INC. (JP) | 1998-07-08 | — | — | EP | disclosed |
| US-5230854-A | Method for removal of spinning solvent from spun fiber | ALLIED-SIGNAL INC. (US) | 1993-07-27 | — | — | US | disclosed |
| JP-H0525269-A | POLYHEXAMETHYLENEADIPAMIDE CONTAINING SMALL AMOUNT OF TRIAMINE AND ITS PRODUCTION | ASAHI CHEM IND CO LTD | 1993-02-02 | — | — | JP | disclosed |
| JP-S60217238-A | CONTINUOUS PRODUCTION OF POLYCAPROAMIDE COPOLYMER | TORAY IND INC | 1985-10-30 | — | — | JP | disclosed |
| US-4089836-A | Process for the coloration of polyamides with pigments derived from carboxyamido-polyimides | PRODUITS CHIMIQUES UGINE KUHLMANN (FR) | 1978-05-16 | — | — | US | disclosed |
| US-4019866-A | Recirculating reaction apparatus for continuous preparation of a polyamide | DU PONT OF CANADA LIMITED (CA) | 1977-04-26 | — | — | US | disclosed |
| US-4002591-A | Coloration of linear polymers by co-polycondensation with pigments | PRODUITS CHIMIQUES UGINE KUHLMANN (FR) | 1977-01-11 | — | — | US | disclosed |