Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 7/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.45 |
| ▸ | CLK1 | P49759 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29911333 | 0.88 | RAB9A (0.53) | RAB9AGAANPC1MAPTSMN1; SMN2 | |
| SCHEMBL29660366 | 0.83 | RAB9A (0.67) | RAB9AGAANPC1MAPTSMN1; SMN2 | |
| SCHEMBL29660348 | 0.82 | RAB9A (0.62) | RAB9AGAANPC1MAPTSMN1; SMN2 | |
| SCHEMBL29911191 | 0.82 | ALDH1A1 (0.51) | RAB9AGAANPC1MAPTSMN1; SMN2 | |
| SCHEMBL29911227 | 0.81 | MMP13 (0.53) | RAB9AGAANPC1MAPTSMN1; SMN2 | |
| SCHEMBL22939614 | 0.80 | RAB9A (0.53) | RAB9AGAANPC1MAPTSMN1; SMN2 | |
| SCHEMBL29911283 | 0.79 | RAB9A (0.51) | RAB9AGAANPC1MAPTSMN1; SMN2 | |
| SCHEMBL29911141 | 0.79 | RAB9A (0.54) | RAB9AGAANPC1MAPTSMN1; SMN2 | |
| SCHEMBL22939582 | 0.78 | RAB9A (0.53) | RAB9AGAANPC1MAPTSMN1; SMN2 | |
| SCHEMBL29911367 | 0.78 | RAB9A (0.60) | RAB9AGAANPC1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021019051-A1 | INHIBITORS OF HUMAN ATGL | Karl-Franzens-Universität Graz (AT) | 2021-02-04 | — | — | WO | disclosed |